(Q30486747)

18 August 2017

Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells (English)

1 reference

18 August 2017

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Melissa Uccellini

7

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John Cambier

object named as

John C Cambier

9

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author name string

Shannon K O'Neill

1

1 reference

18 August 2017

Margaret L Veselits

2

1 reference

18 August 2017

Miao Zhang

3

1 reference

18 August 2017

Christine Labno

4

1 reference

18 August 2017

Yanxia Cao

5

1 reference

18 August 2017

Alison Finnegan

6

1 reference

18 August 2017

Maria-Luisa Alegre

8

1 reference

18 August 2017

Marcus R Clark

10

1 reference

18 August 2017

language of work or name

English

0 references

publication date

30 March 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

106

1 reference

18 August 2017

15

1 reference

18 August 2017

6262-6267

1 reference

describes a project that uses

18 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2662959/fullTextXML

inferred from PubMed Central ID database lookup

cites work

T cell-independent and toll-like receptor-dependent antigen-driven activation of autoreactive B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Cathepsins are required for Toll-like receptor 9 responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Ubiquitinylation of Ig beta dictates the endocytic fate of the B cell antigen receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Cooperation of Toll-like receptor signals in innate immune defence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

A guided tour into subcellular colocalization analysis in light microscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

p38 MAP kinase mediates stress-induced internalization of EGFR: implications for cancer chemotherapy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kappa B in B cell clonal anergy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Cellular and genetic mechanisms of self tolerance and autoimmunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Defective B cell tolerance checkpoints in systemic lupus erythematosus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

B-cell antigen receptor signaling requirements for targeting antigen to the MHC class II presentation pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

The stress-induced MAP kinase p38 regulates endocytic trafficking via the GDI:Rab5 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

The control and facilitation of MHC class II antigen processing by the BCR.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II molecules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

B cell antigen receptor desensitization: disruption of receptor coupling to tyrosine kinase activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Genetic and structural evidence for antigen selection of anti-DNA antibodies.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Separation of subcellular compartments containing distinct functional forms of MHC class II

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662959

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Identification of anergic B cells within a wild-type repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Breakdown of self-tolerance in anergic B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

21 January 2018

DNA drives autoimmunity

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0812922106

Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling

21 January 2018

1 reference

12 December 2020

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

1 reference

12 December 2020

Activation of autoreactive B cells by CpG dsDNA

1 reference

12 December 2020

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0812922106

1 reference

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

19332776

1 reference