(Q30505101)

25 September 2017

Polyfunctional responses by human T cells result from sequential release of cytokines (English)

1 reference

25 September 2017

Douglas A. Lauffenburger

series ordinal

5

object named as

Douglas A Lauffenburger

1 reference

25 September 2017

4

David A Hafler

1 reference

25 September 2017

3

Elizabeth M Bradshaw

1 reference

25 September 2017

Qing Han

1

1 reference

25 September 2017

Neda Bagheri

series ordinal

2

1 reference

25 September 2017

J Christopher Love

series ordinal

6

1 reference

25 September 2017

language of work or name

English

0 references

publication date

12 December 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

25 September 2017

1 reference

25 September 2017

109

1 reference

25 September 2017

5

1 reference

25 September 2017

1607-1612

1 reference

A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Heterogeneity and plasticity of T helper cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Plasticity of CD4+ T cell lineage differentiation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Digital signaling and hysteresis characterize ras activation in lymphoid cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Systems biology of innate immunity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Multiplexed Elispot assay.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Phenotype and function of human T lymphocyte subsets: consensus and issues

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Variability and robustness in T cell activation from regulated heterogeneity in protein levels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Nongenetic individuality in the host-phage interaction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

T-cell quality in memory and protection: implications for vaccine design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Polyfunctional T cell responses are a hallmark of HIV-2 infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Digital NFATc2 activation per cell transforms graded T cell receptor activation into an all-or-none IL-2 expression.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Immunization with vaccinia virus induces polyfunctional and phenotypically distinctive CD8(+) T cell responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Robustness trade-offs and host-microbial symbiosis in the immune system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Bacterial persistence as a phenotypic switch

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Functional heterogeneity of cytokines and cytolytic effector molecules in human CD8+ T lymphocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

A novel transcription factor, T-bet, directs Th1 lineage commitment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Expression and kinetics of cytokines determined by intracellular staining using flow cytometry.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Mechanisms of T cell activation by the calcium ionophore ionomycin.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

Stochastic switching as a survival strategy in fluctuating environments

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277116

T-cell antigen receptor signal transduction

26 November 2018

1 reference

12 December 2020

Seventeen-colour flow cytometry: unravelling the immune system

1 reference

12 December 2020

Visualization of antigen-specific T cell activation and cytokine expression in vivo

1 reference

12 December 2020

Cytokine detection by multiplex technology useful for assessing antigen specific cytokine profiles and kinetics in whole blood cultured up to seven days

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1117194109

1 reference

25 September 2017

0 references

1 reference

25 September 2017

PubMed publication ID

22160692

1 reference