(Q30513719)

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Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies (English)

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Europe PubMed Central

PMC publication ID

11 August 2017

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Marian Beekman

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Kaare Christensen

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Almut Nebel

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11 August 2017

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11 August 2017

Rudi Westendorp

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Rudi G J Westendorp

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Stefan Schreiber

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Stefan Schreiber

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Matt McGue

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H. Eka D. Suchiman

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H Eka D Suchiman

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James W Vaupel

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11 August 2017

Anton J M de Craen

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Anton J M de Craen

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11 August 2017

Mikael Thinggaard

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Mikael Thinggaard

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11 August 2017

Rabea Kleindorp

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Rabea Kleindorp

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11 August 2017

Tinna Stevnsner

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Tinna Stevnsner

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11 August 2017

Vilhelm A. Bohr

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Vilhelm A Bohr

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author name string

Lene Christiansen

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11 August 2017

publication date

3 March 2012

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11 August 2017

Experimental Gerontology

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11 August 2017

47

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Europe PubMed Central

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11 August 2017

5

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11 August 2017

379-387

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Europe PubMed Central

PMC publication ID

11 August 2017

Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways

1 reference

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20 June 2018

The genetic component of human longevity: analysis of the survival advantage of parents and siblings of Italian nonagenarians.

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20 June 2018

Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334439

20 June 2018

Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334439

20 June 2018

Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334439

20 June 2018

Joint influence of small-effect genetic variants on human longevity

1 reference

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20 June 2018

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study

1 reference

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20 June 2018

Progeria syndromes and ageing: what is the connection?

1 reference

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20 June 2018

Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer

1 reference

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20 June 2018

The genetics of ageing

1 reference

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20 June 2018

Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease.

1 reference

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20 June 2018

Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations.

1 reference

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20 June 2018

Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations

1 reference

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20 June 2018

Human genetic variations: Beacons on the pathways to successful ageing

1 reference

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20 June 2018

Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

1 reference

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20 June 2018

Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.

1 reference

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20 June 2018

Association of FOXO3A variation with human longevity confirmed in German centenarians

1 reference

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20 June 2018

Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis

1 reference

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20 June 2018

Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival

1 reference

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20 June 2018

FOXO3A genotype is strongly associated with human longevity

1 reference

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20 June 2018

Genes encoding longevity: from model organisms to humans

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20 June 2018

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study

1 reference

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20 June 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

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20 June 2018

Immunogenetics, gender, and longevity.

1 reference

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20 June 2018

The quest for genetic determinants of human longevity: challenges and insights

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20 June 2018

Suppression of aging in mice by the hormone Klotho

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20 June 2018

Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging

1 reference

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20 June 2018

No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans

1 reference

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20 June 2018

Variation in the human TP53 gene affects old age survival and cancer mortality.

1 reference

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20 June 2018

Haploview: analysis and visualization of LD and haplotype maps

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20 June 2018

The Danish Twin Registry: 127 birth cohorts of twins

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20 June 2018

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

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20 June 2018

p53 mutant mice that display early ageing-associated phenotypes

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20 June 2018

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

1 reference

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20 June 2018

Do men and women follow different trajectories to reach extreme longevity? Italian Multicenter Study on Centenarians (IMUSCE).

1 reference

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20 June 2018

Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae

1 reference

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20 June 2018

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3334439

20 June 2018

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

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20 June 2018

Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition

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20 June 2018

The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900.

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20 June 2018

A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians.

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26 November 2018

Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study.

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26 November 2018

Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity

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26 November 2018

Variants within the ghrelin gene--association with HDL-cholesterol, but not with body mass index.

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26 November 2018

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26 November 2018

Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

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26 November 2018

Association between the MLH1 gene and longevity.

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26 November 2018

Genetic influence on human lifespan and longevity.

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26 November 2018

Reduced insulin/IGF-1 signalling and human longevity.

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26 November 2018

Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity

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26 November 2018

Long-lived Drosophila with overexpressed dFOXO in adult fat body

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26 November 2018

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

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26 November 2018

A high response is not essential to prevent selection bias: results from the Leiden 85-plus study.

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26 November 2018

The Danish 1905 cohort: a genetic-epidemiological nationwide survey.

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26 November 2018

Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans

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26 November 2018

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Genes and longevity: lessons from studies of centenarians

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12 December 2020

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Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis

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12 December 2020

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An integrated system for high throughput TaqManTM based SNP genotyping

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12 December 2020

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DNA damage recognition and repair capacities in human naïve and memory T cells from peripheral blood of young and elderly subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22406557

12 December 2020

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Paraoxonase 1 polymorphisms and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/22406557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical theory of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/22406557

12 December 2020

based on heuristic

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Identifiers

10.1016/J.EXGER.2012.02.010

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

0 references

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