(Q30516504)

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Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

oligodendrocyte

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based on heuristic

inferred from title

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based on heuristic

inferred from title

multiple system atrophy

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

4

object named as

Werner Poewe

1 reference

Europe PubMed Central

18 October 2017

PMC publication ID

5

object named as

Gregor K Wenning

1 reference

Europe PubMed Central

18 October 2017

PMC publication ID

Christian Humpel

3

object named as

Christian Humpel

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Nadia Stefanova

1

object named as

Nadia Stefanova

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

author name string

Walter A Kaufmann

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

publication date

11 April 2012

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Acta Neuropathologica

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

124

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Europe PubMed Central

PMC publication ID

18 October 2017

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

51-65

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3377902/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1007/s00401-012-0977-5

0 references

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Targeted overexpression of human alpha-synuclein in oligodendroglia induces lesions linked to MSA-like progressive autonomic failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Demyelination increases axonal stationary mitochondrial size and the speed of axonal mitochondrial transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Papp-Lantos inclusions and the pathogenesis of multiple system atrophy: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Multiple system atrophy: an update.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

SNCA variants are associated with increased risk for multiple system atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Intermediate filament transcription in astrocytes is repressed by proteasome inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Multiple system atrophy: a primary oligodendrogliopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Axon-glial signaling and the glial support of axon function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Immunolocalization of BK channels in hippocampal pyramidal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Proteasome inhibition and Parkinson's disease modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Morphometric study on cytoskeletal components of neuronal and astroglial cells after chronic CB1 agonist treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Animal models of multiple system atrophy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Gait dynamics in mouse models of Parkinson's disease and Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Alpha-synuclein-positive structures induced in leupeptin-infused rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Axonal neuregulin-1 regulates myelin sheath thickness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Proteasome inhibition: a new anti-inflammatory strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

Synaptic loss reflected by secretoneurin-like immunoreactivity in the human hippocampus in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

If you assume, you can make an ass out of u and me': a decade of the disector for stereological counting of particles in 3D space

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377902

20 June 2018

A comparison of changes in proteasomal subunit expression in the substantia nigra in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

alpha-Synuclein fibrils constitute the central core of oligodendroglial inclusion filaments in multiple system atrophy.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Degeneration of neurons and glia in the Niemann-Pick C mouse is unrelated to the low-density lipoprotein receptor

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Proteasome inhibitor does not enhance MPTP neurotoxicity in mice

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Gene expression changes in postmortem tissue from the rostral pons of multiple system atrophy patients.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Proteasome inhibitors prevent cisplatin-induced mitochondrial release of apoptosis-inducing factor and markedly ameliorate cisplatin nephrotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Lack of nigrostriatal pathology in a rat model of proteasome inhibition.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Electron microscopy of the mouse central nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Chronic systemic treatment with a high-dose proteasome inhibitor in mice produces akinesia unrelated to nigrostriatal degeneration.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Ubiquitin enzymes, ubiquitin and proteasome activity in blood mononuclear cells of MCI, Alzheimer and Parkinson patients

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Reproducible nigral cell loss after systemic proteasomal inhibitor administration to rats.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Microglial activation mediates neurodegeneration related to oligodendroglial α-synucleinopathy: Implications for multiple system atrophy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-0977-5

21 January 2018

Slowly progressive axonal degeneration in a rat model of chronic, nonimmune-mediated demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/22491959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The temporal progression of the myelination defect in the taiep rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22491959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitor model of Parkinson's disease in mice is confounded by neurotoxicity of the ethanol vehicle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22491959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths

1 reference

https://pubmed.ncbi.nlm.nih.gov/22491959

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00401-012-0977-5

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

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