(Q30524899)

12 August 2017

LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors (English)

1 reference

12 August 2017

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1 reference

14

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23 June 2017

Brittany Dugger

8

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Iryna Prots

object named as

Iryna Prots

10

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Beate Winner

object named as

Beate Winner

9

0 references

Matthew J. Farrer

object named as

Matthew J Farrer

16

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author name string

Kelly M Hinkle

1

1 reference

12 August 2017

Mei Yue

2

1 reference

12 August 2017

Bahareh Behrouz

3

1 reference

12 August 2017

Justus C Dächsel

4

1 reference

12 August 2017

Sarah J Lincoln

5

1 reference

12 August 2017

Erin E Bowles

6

1 reference

12 August 2017

Joel E Beevers

7

1 reference

12 August 2017

Caroline B Kent

11

1 reference

12 August 2017

Kenya Nishioka

12

1 reference

12 August 2017

Wen-Lang Lin

13

1 reference

12 August 2017

Christopher J Janus

15

1 reference

12 August 2017

Heather L Melrose

17

1 reference

12 August 2017

language of work or name

1 reference

30 May 2012

1 reference

Molecular Neurodegeneration

12 August 2017

1 reference

12 August 2017

7

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12 August 2017

25

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3441373/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1750-1326-7-25

0 references

cites work

Loss of leucine-rich repeat kinase 2 causes age-dependent bi-phasic alterations of the autophagy pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

LRRK2 function on actin and microtubule dynamics in Parkinson disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

A comparative study of Lrrk2 function in primary neuronal cultures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Progression of dopaminergic dysfunction in a LRRK2 kindred: a multitracer PET study

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Behavioural phenotyping of transgenic mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Dynamic and redundant regulation of LRRK2 and LRRK1 expression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Dentate gyrus neurogenesis and depression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Adult hippocampal neurogenesis in depression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Lrrk2 G2385R is an ancestral risk factor for Parkinson's disease in Asia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Identification of a common genetic risk variant (LRRK2 Gly2385Arg) in Parkinson's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Screening for Lrrk2 G2019S and clinical comparison of Tunisian and North American Caucasian Parkinson's disease families

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Deletion of the triplet repeat encoding polyglutamine within the mouse Huntington's disease gene results in subtle behavioral/motor phenotypes in vivo and elevated levels of ATP with cellular senescence in vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Gait dynamics in mouse models of Parkinson's disease and Huntington's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Doublecortin expression levels in adult brain reflect neurogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Different data from different labs: lessons from studies of gene-environment interaction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Extended analysis of path data from mutant mice using the public domain software Wintrack

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Thigmotaxis as a test for anxiolytic activity in rats.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Anxiety disorders in familial parkinsonism.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

14 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Dopamine turnover increases in asymptomatic LRRK2 mutations carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Positron emission tomography changes in PARK1 mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

LRRK2 expression linked to dopamine-innervated areas

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Distribution of PINK1 and LRRK2 in rat and mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Methamphetamine-induced structural plasticity in the dorsal striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Non-motor behavioural impairments in parkin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Genetically modified mice and cognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Motor learning in Ts65Dn mice, a model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Ethanol's effects on gait dynamics in mice investigated by ventral plane videography

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Profiling changes in gait dynamics resulting from progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nigrostriatal lesioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

Inhibitory effects of ascorbic acid on dopamine uptake by rat striatal synaptosomes: relationship to lipid peroxidation and oxidation of protein sulfhydryl groups.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-25

(123)I-FP-CIT SPET striatal uptake in parkinsonian patients with the alpha-synuclein (G209A) mutation A.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Testing association between LRRK2 and Parkinson's disease and investigating linkage disequilibrium

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

"In vitro" effect of some 5-hydroxy-indolalkylamine derivatives on monoamine uptake system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3441373

Endogenous DA-mediated feedback inhibition of DA neurons: involvement of both D(1)- and D(2)-like receptors

26 November 2018

1 reference

12 December 2020

A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan

1 reference

12 December 2020

Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study

1 reference

12 December 2020

PET studies of parkinsonism associated with mutation in the alpha-synuclein gene

1 reference

12 December 2020

Identifiers

DOI

10.1186/1750-1326-7-25

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

1 reference