(Q34454883)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

Christian Johannes Gloeckner

14 February 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Michaela Bauer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

9

Norbert Kinkl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

10

Marius Ueffing

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1

Andrea Meixner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Karsten Boldt

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Marleen Van Troys

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Jarrod A Marto

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Christophe Ampe

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

publication date

27 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

Molecular & Cellular Proteomics

14 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

M110.001172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

14 February 2020

NeuronJ

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3013447/fullTextXML

24 May 2022

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3013447/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Pathway Palette: a rich internet application for peptide-, protein- and network-oriented analysis of MS data

6 July 2018

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Actin, a central player in cell shape and movement

6 July 2018

1 reference

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Non-muscle myosin II takes centre stage in cell adhesion and migration

6 July 2018

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LRRK2 in Parkinson's disease: biochemical functions

6 July 2018

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LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

6 July 2018

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Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways

6 July 2018

1 reference

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Lrrk2 phosphorylates alpha synuclein at serine 129: Parkinson disease implications

6 July 2018

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Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

6 July 2018

1 reference

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Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

6 July 2018

1 reference

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Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP

6 July 2018

1 reference

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The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro

6 July 2018

1 reference

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CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

6 July 2018

1 reference

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Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease

6 July 2018

1 reference

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Prevention of interferon-stimulated gene expression using microRNA-designed hairpins

6 July 2018

1 reference

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Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra

6 July 2018

1 reference

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The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player

6 July 2018

1 reference

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A cytoskeletal demolition worker: myosin II acts as an actin depolymerization agent.

6 July 2018

1 reference

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Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons

6 July 2018

1 reference

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A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Actin-binding proteins in nerve cell growth cones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Leucine-rich repeat kinase 2 associates with lipid rafts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Protein interaction screening by quantitative immunoprecipitation combined with knockdown (QUICK).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Kinase activity of mutant LRRK2 mediates neuronal toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Enhancing and confirming the specificity of RNAi experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Data merging for integrated microarray and proteomic analysis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LRRK2 in Parkinson's disease: protein domains and functional insights

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LRRK2: a common pathway for parkinsonism, pathogenesis and prevention?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

BioGRID: a general repository for interaction datasets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Human protein reference database--2006 update

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

6 July 2018

Actin-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Integrated genomic and proteomic analyses of gene expression in Mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The actin cytoskeleton in normal and pathological cell motility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Roc, a Ras/GTPase domain in complex proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Tropomodulins: life at the slow end.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Q-Gene: processing quantitative real-time RT-PCR data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Actin binding proteins: regulation of cytoskeletal microfilaments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

EPLIN regulates actin dynamics by cross-linking and stabilizing filaments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The identification of pats1, a novel gene locus required for cytokinesis in Dictyostelium discoideum

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Signaling mechanisms that regulate actin-based motility processes in the nervous system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Rho GTPases in neuronal morphogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

In vivo function of class I myosins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The flightless I protein localizes to actin-based structures during embryonic development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

KEGG: kyoto encyclopedia of genes and genomes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Extraction and characterization of the insecticidal toxin hirsutellin A produced by Hirsutella thompsonii var. thompsonii

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LRRK2 gene variation and its contribution to Parkinson disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Rab35 regulates neurite outgrowth and cell shape.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

LRRK2: bridging the gap between sporadic and hereditary Parkinson's disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Retraction of synapses and dendritic spines induced by off-target effects of RNA interference.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Distribution of PINK1 and LRRK2 in rat and mouse brain

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3013447

The interaction of plectin with actin: evidence for cross-linking of actin filaments by dimerization of the actin-binding domain of plectin

27 October 2018

1 reference

12 December 2020

Actin dynamics: tropomyosin provides stability

1 reference

12 December 2020

1 reference

12 December 2020

Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments

1 reference

12 December 2020

Strep/FLAG tandem affinity purification (SF-TAP) to study protein interactions

1 reference

12 December 2020

Identifiers

DOI

10.1074/MCP.M110.001172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20876399%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference