(Q30533331)

15 August 2017

Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal (English)

1 reference

15 August 2017

3

Christopher E Rudd

1 reference

15 August 2017

Yuning Lu

1

1 reference

15 August 2017

Helga Schneider

series ordinal

2

1 reference

15 August 2017

language of work or name

English

0 references

publication date

9 October 2012

1 reference

15 August 2017

11

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based on heuristic

inferred from page(s)

published in

Blood

1 reference

15 August 2017

120

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15 August 2017

23

1 reference

15 August 2017

4560-4570

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3557398/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells

14 July 2018

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Regulatory T cells: mechanisms of differentiation and function

14 July 2018

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A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

14 July 2018

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CD28 co-signaling in the adaptive immune response.

14 July 2018

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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

14 July 2018

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Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy

14 July 2018

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T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes

14 July 2018

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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

14 July 2018

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CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms

14 July 2018

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Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

14 July 2018

1 reference

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Involvement of Rap-1 activation and early termination of immune synapse in CTLA-4-mediated negative signal

14 July 2018

1 reference

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CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo

14 July 2018

1 reference

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CTLA-4 is required by CD4+CD25+ Treg to control CD4+ T-cell lymphopenia-induced proliferation

14 July 2018

1 reference

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Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation

14 July 2018

1 reference

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CTLA-4 control over Foxp3+ regulatory T cell function

14 July 2018

1 reference

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Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy

14 July 2018

1 reference

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Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

14 July 2018

1 reference

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CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3-kinase-independent manner.

14 July 2018

1 reference

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Reversal of the TCR stop signal by CTLA-4

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

14 July 2018

1 reference

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CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function

14 July 2018

1 reference

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Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4.

14 July 2018

1 reference

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14 July 2018

The B7 family revisited

1 reference

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CD28-mediated co-stimulation: a quantitative support for TCR signalling

14 July 2018

1 reference

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Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling

14 July 2018

1 reference

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Adaptors as central mediators of signal transduction in immune cells

14 July 2018

1 reference

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Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation

14 July 2018

1 reference

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CTLA-4 negative signaling via lipid rafts: A new perspective

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Cytotoxic T lymphocyte antigen 4 and CD28 modulate cell surface raft expression in their regulation of T cell function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

14 July 2018

1 reference

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Structural analysis of CTLA-4 function in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Adaptors and molecular scaffolds in immune cell signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Spatiotemporal basis of CTLA-4 costimulatory molecule-mediated negative regulation of T cell activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Expression of CD86 on human islet endothelial cells facilitates T cell adhesion and migration.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

The reverse stop-signal model for CTLA4 function

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

T cell receptor-interacting molecule acts as a chaperone to modulate surface expression of the CTLA-4 coreceptor.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Immunology. Restless T cells sniff and go

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3557398

10.1182/BLOOD-2012-04-421420

26 November 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23047820

1 reference