(Q30746506)

26 June 2017

1 reference

title

Selection of mutations for increased protein stability (English)

1 reference

26 June 2017

2

Vincent G H Eijsink

1 reference

26 June 2017

Bertus van den Burg

1

1 reference

26 June 2017

1 August 2002

1 reference

Current Opinion in Biotechnology

26 June 2017

1 reference

26 June 2017

13

1 reference

26 June 2017

4

1 reference

26 June 2017

333-337

1 reference

Studies on protein stability with T4 lysozyme

26 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Design, structure and stability of a hyperthermophilic protein variant

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Directed evolution of a thermostable esterase.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

In-vitro selection of highly stabilized protein variants with optimized surface

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Temperature adaptation of enzymes: lessons from laboratory evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Thermophilic adaptation of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Hyperthermophilic enzymes: sources, uses, and molecular mechanisms for thermostability

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Structural determinants of the stability of thermolysin-like proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Molecular determinants of xylose isomerase thermal stability and activity: analysis of thermozymes by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Two exposed amino acid residues confer thermostability on a cold shock protein

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

A single point mutation (Glu85Arg) increases the stability of the thioredoxin from Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Structural differences between mesophilic, moderately thermophilic and extremely thermophilic protein subunits: results of a comprehensive survey

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Protein thermostability above 100 degreesC: a key role for ionic interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Probing the role of oligomerization in the high thermal stability of Pyrococcus furiosus ornithine carbamoyltransferase by site-specific mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Tiny TIM: a small, tetrameric, hyperthermostable triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Structural basis for thermophilic protein stability: structures of thermophilic and mesophilic malate dehydrogenases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Increasing the thermal stability of an oligomeric protein, beta-glucuronidase.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

The stability of salt bridges at high temperatures: implications for hyperthermophilic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Electrostatic contributions to the stability of hyperthermophilic proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

To charge or not to charge?

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Increasing protein stability by altering long-range coulombic interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Rational Modification of Protein Stability by the Mutation of Charged Surface Residues†

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Electrostatic stabilization of a thermophilic cold shock protein

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Electrostatics significantly affect the stability of designed homeodomain variants

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

A test of proposed rules for helix capping: Implications for protein design

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

From DNA sequence to improved functionality: using protein sequence comparisons to rapidly design a thermostable consensus phytase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Ancestral residues stabilizing 3-isopropylmalate dehydrogenase of an extreme thermophile: experimental evidence supporting the thermophilic common ancestor hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Packing is a key selection factor in the evolution of protein hydrophobic cores

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Improved biocatalysts by directed evolution and rational protein design

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Enzyme engineering: rational redesign versus directed evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Combinatorial and computational challenges for biocatalyst design

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Directed evolution converts subtilisin E into a functional equivalent of thermitase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Patterns of adaptation in a laboratory evolved thermophilic enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Expression and stabilization of galactose oxidase in Escherichia coli by directed evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

A structural view of evolutionary divergence

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

In vitro enzyme evolution: the screening challenge of isolating the one in a million

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Selection of stabilized 3-isopropylmalate dehydrogenase of Saccharomyces cerevisiae using the host-vector system of an extreme thermophile, Thermus thermophilus.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Engineering an enzyme to resist boiling

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Mutant barley (1-->3,1-->4)-beta-glucan endohydrolases with enhanced thermostability

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

The effect of proline insertions on the thermostability of a barley alpha-glucosidase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

The refined crystal structure of Bacillus cereus oligo-1,6-glucosidase at 2.0 A resolution: structural characterization of proline-substitution sites for protein thermostabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Increasing protein stability by polar surface residues: domain-wide consequences of interactions within a loop

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

WHAT IF: a molecular modeling and drug design program

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Protein aggregation: folding aggregates, inclusion bodies and amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Aggregation events occur prior to stable intermediate formation during refolding of interleukin 1beta

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

The initial step of the thermal unfolding of 3-isopropylmalate dehydrogenase detected by the temperature-jump Laue method

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Stabilization of pancreatic ribonuclease A by immobilization on Sepharose-linked antibodies that recognize the labile region of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Differentiation between conformational and autoproteolytic stability of the neutral protease from Bacillus stearothermophilus containing an engineered disulfide bond

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Breakdown in the relationship between thermal and thermodynamic stability in an interleukin-1 beta point mutant modified in a surface loop

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Early steps in the unfolding of thermolysin-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

Reverse hydrophobic effects relieved by amino-acid substitutions at a protein surface.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2802%2900325-7

7 January 2021

10.1016/S0958-1669(02)00325-7

Identifiers

DOI

1 reference

26 June 2017

1 reference

PubMed ID

12323355