(Q34070088)

30 July 2017

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title

Temperature adaptation of enzymes: lessons from laboratory evolution (English)

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30 July 2017

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Wintrode PL

1

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30 July 2017

Arnold FH

series ordinal

2

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30 July 2017

publication date

1 January 2000

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Advances in Protein Chemistry

30 July 2017

published in

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30 July 2017

volume

55

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30 July 2017

page(s)

161-225

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Finding and using hyperthermophilic enzymes.

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor

1 reference

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7 January 2021

Serial increase in the thermal stability of 3-isopropylmalate dehydrogenase from Bacillus subtilis by experimental evolution

1 reference

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7 January 2021

Mutational effects on protein stability

1 reference

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7 January 2021

Stabilization of Escherichia coli isopropylmalate dehydrogenase by single amino acid substitution

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7 January 2021

When blind is better: protein design by evolution

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7 January 2021

Closed structure of phosphoglycerate kinase from Thermotoga maritima reveals the catalytic mechanism and determinants of thermal stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Lactate dehydrogenase from the hyperthermophilic bacterium thermotoga maritima: the crystal structure at 2.1 A resolution reveals strategies for intrinsic protein stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Protein stability parameters measured by hydrogen exchange

1 reference

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7 January 2021

Protein folding intermediates: native-state hydrogen exchange

1 reference

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7 January 2021

Comparing the thermodynamic stabilities of a related thermophilic and mesophilic enzyme

1 reference

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7 January 2021

Deciphering the message in protein sequences: tolerance to amino acid substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Incorporation of a stabilizing Ca(2+)-binding loop into subtilisin BPN'

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Acid and thermal denaturation of barnase investigated by molecular dynamics simulations

1 reference

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7 January 2021

Hydrogen tunneling in enzyme reactions

1 reference

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7 January 2021

Stability and Activity of Mesophilic Subtilisin E and Its Thermophilic Homolog: Insights from Molecular Dynamics Simulations

1 reference

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7 January 2021

Tolerance of a protein to multiple polar-to-hydrophobic surface substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Stability and folding of dihydrofolate reductase from the hyperthermophilic bacterium Thermotoga maritima

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

A correlation between protein thermostability and resistance to proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Correlation of hydrogen exchange behaviour and thermal stability of lysozyme

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https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Dominant forces in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Principles of protein folding--a perspective from simple exact models.

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7 January 2021

Nothing in Biology Makes Sense except in the Light of Evolution

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7 January 2021

Dynamical transition of myoglobin revealed by inelastic neutron scattering

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7 January 2021

The stability of salt bridges at high temperatures: implications for hyperthermophilic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Activation of chicken liver dihydrofolate reductase by urea and guanidine hydrochloride is accompanied by conformational change at the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Psychrophilic enzymes: molecular basis of cold adaptation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Thermodynamic stability of a cold-active alpha-amylase from the Antarctic bacterium Alteromonas haloplanctis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structure and stability of thermophilic enzymes. Studies on thermolysin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

The Energy Landscapes and Motions of Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Statistical thermodynamic linkage between conformational and binding equilibria.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Psychrophilic enzymes: a thermodynamic challenge

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Tryptophan phosphorescence study of enzyme flexibility and unfolding in laboratory-evolved thermostable esterases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Tolerance of a protein helix to multiple alanine and valine substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Solution structure of ferredoxin from the thermophilic cyanobacterium Synechococcus elongatus and its thermostability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Do salt bridges stabilize proteins? A continuum electrostatic analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

2.0 A structure of indole-3-glycerol phosphate synthase from the hyperthermophile Sulfolobus solfataricus: possible determinants of protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structure-based calculation of the equilibrium folding pathway of proteins. Correlation with hydrogen exchange protection factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Thermodynamics of complex formation between nicotinamide adenine dinucleotide and pig skeletal muscle lactate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Protein conformational stabilities can be determined from hydrogen exchange rates

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

A stable intermediate in the thermal unfolding process of a chimeric 3-isopropylmalate dehydrogenase between a thermophilic and a mesophilic enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Protein structure and function at low temperatures.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

The stability of proteins in extreme environments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

3D structural information as a guide to protein engineering using genetic selection

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Some factors in the interpretation of protein denaturation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Evolutionary Rate at the Molecular Level

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

The crystal structure of holo-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima at 2.5 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Dynamics and unfolding pathways of a hyperthermophilic and a mesophilic rubredoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Alternative packing arrangements in the hydrophobic core of λrepresser

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

The role of internal packing interactions in determining the structure and stability of a protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Folding funnels and binding mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Small structural changes account for the high thermostability of 1[4Fe-4S] ferredoxin from the hyperthermophilic bacterium Thermotoga maritima

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structural and genetic analysis of protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Guanidinium chloride induction of partial unfolding in amide proton exchange in RNase A.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Analysis of the relationship between enzyme activity and its internal motion using nuclear magnetic resonance: 15N relaxation studies of wild-type and mutant lysozyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Exploring nonnatural evolutionary pathways by saturation mutagenesis: rapid improvement of protein function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Directed evolution study of temperature adaptation in a psychrophilic enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Directed evolution of a para-nitrobenzyl esterase for aqueous-organic solvents

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Functional expression of horseradish peroxidase in Saccharomyces cerevisiae and Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Theory of protein folding: the energy landscape perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Forces contributing to the conformational stability of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Ferredoxin from the hyperthermophile Thermotoga maritima is stable beyond the boiling point of water.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Stabilization of a reaction intermediate as a catalytic device: definition of the functional role of the flexible loop in triosephosphate isomerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Analysis of protein conformational characteristics related to thermostability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Crystalline ribonuclease A loses function below the dynamical transition at 220 K

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Combinatorial cassette mutagenesis as a probe of the informational content of protein sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Engineering thermostability: lessons from thermophilic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Thermodynamic studies of binary and ternary complexes of pig heart lactate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Theory of cooperative transitions in protein molecules. I. Why denaturation of globular protein is a first-order phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Subtilases: the superfamily of subtilisin-like serine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Creating novel enzymes by applied molecular evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Proteins and temperature

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Rapid evolution of a protein in vitro by DNA shuffling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Native protein fluctuations: the conformational-motion temperature and the inverse correlation of protein flexibility with protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Crystal structure of thermitase at 1.4 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Transproteomic evidence of a loop-deletion mechanism for enhancing protein thermostability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Relation between stability, dynamics and enzyme activity in 3-phosphoglycerate kinases from yeast and Thermus thermophilus

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7 January 2021

Protein thermal stability: hydrogen bonds or internal packing?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Role of bound calcium ions in thermostable, proteolytic enzymes. Separation of intrinsic and calcium ion contributions to the kinetic thermal stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Correlation between the amide proton exchange rates and the denaturation temperatures in globular proteins related to the basic pancreatic trypsin inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Amide protein exchange and surface conformation of the basic pancreatic trypsin inhibitor in solution. Studies with two-dimensional nuclear magnetic resonance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Are buried salt bridges important for protein stability and conformational specificity?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Multiple proline substitutions cumulatively thermostabilize Bacillus cereus ATCC7064 oligo-1,6-glucosidase. Irrefragable proof supporting the proline rule

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Gene from tropical Bacillus sphaericus encoding a protease closely related to subtilisins from Antarctic bacilli

1 reference

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7 January 2021

Structural and mutagenesis studies of leishmania triosephosphate isomerase: a point mutation can convert a mesophilic enzyme into a superstable enzyme without losing catalytic power

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Structural stability and internal motions of Escherichia coli ribonuclease HI: 15N relaxation and hydrogen-deuterium exchange analyses

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Insights into the molecular basis of thermal stability from the analysis of ion-pair networks in the glutamate dehydrogenase family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Optimization of DNA shuffling for high fidelity recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Directed evolution converts subtilisin E into a functional equivalent of thermitase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Molecular evolution by staggered extension process (StEP) in vitro recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

1 reference

7 January 2021

Structural and energetic consequences of disruptive mutations in a protein core

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Subtilisin from psychrophilic antarctic bacteria: characterization and site-directed mutagenesis of residues possibly involved in the adaptation to cold

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Stability of proteins: small globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

Engineering of a cold-adapted protease by sequential random mutagenesis and a screening system.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

A cold-adapted protease engineered by experimental evolution system

1 reference

https://api.crossref.org/works/10.1016%2FS0065-3233%2801%2955004-4

7 January 2021

10.1016/S0065-3233(01)55004-4

Identifiers

DOI

1 reference

release_rrnjctajdbg3xerttlyiktfdyu

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rrnjctajdbg3xerttlyiktfdyu

24 November 2022

mapped directly with Wikidata item

1 reference