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Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes.
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Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
title
Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
main subject
phosphorylation
1 reference
based on heuristic
inferred from title
adipocyte
1 reference
based on heuristic
inferred from title
author
Lars Rönnstrand
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author name string
Olga Göransson
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
Svante Resjö
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
Vincent Manganiello
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
Eva Degerman
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
publication date
1 February 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
number of pages
8
1 reference
based on heuristic
inferred from page(s)
published in
Cellular Signalling
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
175-182
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
cites work
Cellular survival: a play in three Akts
1 reference
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reference URL
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7 January 2021
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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.
1 reference
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Crossref
reference URL
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7 January 2021
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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
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7 January 2021
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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a second form of rac protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of translocation in the activation and function of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor stimulation of hematopoietic cells leads to membrane translocation of AKT1 protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation of protein kinase B by insulin and IGF-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-induced phosphorylation and activation of phosphodiesterase 3B in rat adipocytes: possible role for protein kinase B but not mitogen-activated protein kinase or p70 S6 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms involved in the antilipolytic action of insulin: phosphorylation and activation of a particulate adipocyte cAMP phosphodiesterase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the antilipolytic action of insulin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that insulin and isoprenaline activate the cGMP-inhibited low-Km cAMP phosphodiesterase in rat fat cells by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes. Studies using the selective inhibitor wortmannin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
[2] Regulation of hormone-sensitive lipase activity in adipose tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of protein kinase B in rat adipocytes by insulin, vanadate, and peroxovanadate. Membrane translocation in response to peroxovanadate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin increases the association of Akt-2 with Glut4-containing vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0898-6568%2801%2900242-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0898-6568(01)00242-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
PubMed publication ID
11781143
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11781143
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781143%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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