(Q30832957)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

A data-driven approach to modeling the tripartite structure of multidrug resistance efflux pumps (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

main subject

multiple drug resistance

0 references

author

S Gnanakaran

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Joshua L Phillips

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

18 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

83

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

46-65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

Three's company: component structures bring a closer view of tripartite drug efflux pumps.

21 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Antibiotic efflux pumps in Gram-negative bacteria: the inhibitor response strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Trinity revealed: Stoichiometric complex assembly of a bacterial multidrug efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Multidrug efflux transporter, AcrB--the pumping mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Structural and dynamical insights into the opening mechanism of P. aeruginosa OprM channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Crystal structure of the multidrug exporter MexB from Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

The assembled structure of a complete tripartite bacterial multidrug efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Structural and functional diversity of bacterial membrane fusion proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Assembly and Channel Opening of Outer Membrane Protein in Tripartite Drug Efflux Pumps of Gram-negative Bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Drug transport mechanism of the AcrB efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Covalently linked trimer of the AcrB multidrug efflux pump provides support for the functional rotating mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Comparative protein structure modeling using MODELLER

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Statistical potential for assessment and prediction of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Structural basis for the inhibition of bacterial multidrug exporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Crystal structure of AcrB complexed with linezolid at 3.5 Å resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

A global geometric framework for nonlinear dimensionality reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Validating clustering of molecular dynamics simulations using polymer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Cryo-Transmission Electron Microscopy of Frozen-Hydrated Sections ofEscherichia coliandPseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Structure and operation of bacterial tripartite pumps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Disclosure of the mycobacterial outer membrane: cryo-electron tomography and vitreous sections reveal the lipid bilayer structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

The outer membrane TolC-like channel HgdD is part of tripartite resistance-nodulation-cell division (RND) efflux systems conferring multiple-drug resistance in the Cyanobacterium Anabaena sp. PCC7120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Functional rotation of the transporter AcrB: insights into drug extrusion from simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

A coordinated network of transporters with overlapping specificities provides a robust survival strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

A periplasmic drug-binding site of the AcrB multidrug efflux pump: a crystallographic and site-directed mutagenesis study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Vestibules are part of the substrate path in the multidrug efflux transporter AcrB of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

Mutations in the central cavity and periplasmic domain affect efflux activity of the resistance-nodulation-division pump EmhB from Pseudomonas fluorescens cLP6a

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROT.24632

21 January 2018

Identifiers

DOI

10.1002/PROT.24632

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24957790%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference