(Q30846580)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

0 references

1 reference

1 reference

Annachiara De Sandre-Giovannoli

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Claire L Navarro

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Lino Ferreira

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Nicolas Levy

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Xavier Nissan

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

author name string

S Blondel

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

A-L Egesipe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

P Picardi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

A-L Jaskowiak

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

M Notarnicola

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

J Ragot

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

J Tournois

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

A Le Corf

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

B Brinon

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

P Poydenot

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

P Georges

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

P R Pitrez

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

G Bollot

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

C Bauvais

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

D Laustriat

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

A Mejat

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

M Bifulco

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

M Peschanski

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

publication date

18 February 2016

1 reference

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8 March 2020

published in

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

page(s)

e2105

1 reference

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Creative Commons Attribution 4.0 International

8 March 2020

copyright license

start time

1 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), J

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

14 July 2018

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High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

14 July 2018

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CYT387, a novel JAK2 inhibitor, induces hematologic responses and normalizes inflammatory cytokines in murine myeloproliferative neoplasms

14 July 2018

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Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria

14 July 2018

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A small molecule primes embryonic stem cells for differentiation

14 July 2018

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4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors

14 July 2018

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Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

14 July 2018

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High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells

14 July 2018

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Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

14 July 2018

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Phenotype and course of Hutchinson-Gilford progeria syndrome

14 July 2018

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14 July 2018

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A novel quinoline, MT477: suppresses cell signaling through Ras molecular pathway, inhibits PKC activity, and demonstrates in vivo anti-tumor activity against human carcinoma cell lines

14 July 2018

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Efficacy, Pharmacokinetics, and Metabolism of Tetrahydroquinoline Inhibitors of Plasmodium falciparum Protein Farnesyltransferase

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition

14 July 2018

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AMN107, a novel aminopyrimidine inhibitor of p190 Bcr-Abl activation and of in vitro proliferation of Philadelphia-positive acute lymphoblastic leukemia cells

14 July 2018

1 reference

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Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.

14 July 2018

1 reference

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Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy

14 July 2018

1 reference

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Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer

14 July 2018

1 reference

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

14 July 2018

1 reference

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Lamin a truncation in Hutchinson-Gilford progeria.

14 July 2018

1 reference

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Differential binding of proteins to peroxisomes in rat hepatoma cells: unique association of enzymes involved in isoprenoid metabolism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

Farnesyl-diphosphate synthase is localized in peroxisomes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

ras oncogenes in human cancer: a review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

Regulation of the mevalonate pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

Structure of rhodotorucine A, a novel lipopeptide, inducing mating tube formation in Rhodosporidium toruloides

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression

14 July 2018

1 reference

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A GAL4-driver line resource for Drosophila neurobiology

21 January 2018

1 reference

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Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

21 January 2018

1 reference

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Protein farnesyltransferase inhibitors exhibit potent antimalarial activity

21 January 2018

1 reference

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QSAR study on tetrahydroquinoline analogues as plasmodium protein farnesyltransferase inhibitors: a comparison of rationales of malarial and mammalian enzyme inhibitory activities for selectivity.

21 January 2018

1 reference

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A phase II trial of high-dose imatinib mesylate for relapsed or refractory c-kit positive and Bcr-Abl negative acute myeloid leukaemia: the AFR-15 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

Foreword: bisphosphonates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

Further insight into mechanism of action of clodronate: inhibition of mitochondrial ADP/ATP translocase by a nonhydrolyzable, adenine-containing metabolite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

Unique Preservation of Neural Cells in Hutchinson- Gilford Progeria Syndrome Is Due to the Expression of the Neural-Specific miR-9 MicroRNA

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399184

WITHDRAWN: Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective

25 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2015.374

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2015.374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

26890144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26890144%20AND%20SRC:MED&resulttype=core&format=json