(Q30938639)

27 June 2017

1 reference

title

Scientific and Regulatory Policy Committee (SRPC) Review: Interpretation and Use of Cell Proliferation Data in Cancer Risk Assessment (English)

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27 June 2017

Charles E Wood

1

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27 June 2017

Renee R Hukkanen

2

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27 June 2017

Radhakrishna Sura

3

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27 June 2017

David Jacobson-Kram

4

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27 June 2017

Thomas Nolte

5

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27 June 2017

Marielle Odin

6

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27 June 2017

Samuel M Cohen

7

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27 June 2017

language of work or name

English

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publication date

22 April 2015

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27 June 2017

published in

Toxicologic Pathology

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27 June 2017

volume

43

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27 June 2017

issue

6

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27 June 2017

page(s)

760-775

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Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats

27 June 2017

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21 January 2018

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Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites

21 January 2018

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Cell cycle dependent expression and stability of the nuclear protein detected by Ki-67 antibody in HL-60 cells

21 January 2018

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Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.

21 January 2018

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Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells

21 January 2018

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Tissue fixation for immunohistochemical detection of proliferating cell nuclear antigen with PC10 monoclonal antibody

21 January 2018

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Treatment of non-small-cell lung cancer with erlotinib or gefitinib

21 January 2018

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Role of cell proliferation in regenerative and neoplastic disease

21 January 2018

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Human carcinogenic risk evaluation: an alternative approach to the two-year rodent bioassay

21 January 2018

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Cell proliferation in carcinogenesis

21 January 2018

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Evaluating the human relevance of chemically induced animal tumors

21 January 2018

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Investigations of rodent urinary bladder carcinogens: collection, processing, and evaluation of urine and bladders

21 January 2018

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Rodent Leydig cell tumorigenesis: a review of the physiology, pathology, mechanisms, and relevance to humans

21 January 2018

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Studies of styrene, styrene oxide and 4-hydroxystyrene toxicity in CYP2F2 knockout and CYP2F1 humanized mice support lack of human relevance for mouse lung tumors

21 January 2018

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State of the art in antigen retrieval for immunohistochemistry.

21 January 2018

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Thiazopyr and thyroid disruption: case study within the context of the 2006 IPCS Human Relevance Framework for analysis of a cancer mode of action.

21 January 2018

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Regulatory Forum opinion piece: image analysis-based cell proliferation studies using electronic images: the CEPA industry working group's proposal

21 January 2018

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Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group

21 January 2018

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Implications of apoptosis for toxicity, carcinogenicity, and risk assessment: fumonisin B(1) as an example

21 January 2018

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Update on artificial sweeteners and bladder cancer

21 January 2018

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Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Cell proliferation rates in common cancer target tissues of B6C3F1 mice and F344 rats: effects of age, gender, and choice of marker.

21 January 2018

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The health risks of saccharin revisited

21 January 2018

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Apoptosis: a review of programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Unbiased stereological method to assess proliferation throughout the subependymal zone

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

21 January 2018

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Evolution of alachlor-induced nasal neoplasms in the Long-Evans rat.

21 January 2018

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Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

21 January 2018

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Chloroform mode of action: implications for cancer risk assessment

21 January 2018

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The functional relationship between in vivo bromodeoxyuridine labeling index and Ki-67 proliferation index in human breast cancer

21 January 2018

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Improved detection of apoptotic cells in archival paraffin sections: immunohistochemistry using antibodies to cleaved caspase 3.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

A general probabilistic model of carcinogenesis: analysis of experimental urinary bladder cancer

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Detecting proliferating cell nuclear antigen in archival rodent tissues

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

21 January 2018

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1177%2F0192623315576005

Hallmarks of Cancer: The Next Generation

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Mode of action in relevance of rodent liver tumors to human cancer risk.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Trastuzumab--mechanism of action and use in clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

CELLULAR PROLIFERATION IN THE MOUSE AS REVEALED BY AUTORADIOGRAPHY WITH TRITIATED THYMIDINE.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Effects of long-term storage on the detection of proteins, DNA, and mRNA in tissue microarray slides

21 January 2018

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In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle

21 January 2018

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Mechanistic considerations in small fish carcinogenicity testing

21 January 2018

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A short history of the initial application of anti-5-BrdU to the detection and measurement of S phase

21 January 2018

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Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity

21 January 2018

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5-Bromo-2-deoxyuridine activates DNA damage signalling responses and induces a senescence-like phenotype in p16-null lung cancer cells

21 January 2018

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Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB1.

21 January 2018

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Cell division versus cell death: a functional model of multistep neoplasia

21 January 2018

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Proliferation assays (BrdU and EdU) on skeletal tissue sections

21 January 2018

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A framework for human relevance analysis of information on carcinogenic modes of action

21 January 2018

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New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis.

21 January 2018

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Early BrdU-responsive genes constitute a novel class of senescence-associated genes in human cells.

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Mutation and cancer: a model for human carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Analysis of cell proliferation data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Evaluation of Cell Proliferation in Rat Tissues with BrdU, PCNA, Ki-67(MIB-5) Immunohistochemistry and In Situ Hybridization for Histone mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Standardized assessment of cell proliferation: the approach of the RITA-CEPA working group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Preservation of immunorecognition by transferring cells from 10% neutral buffered formalin to 70% ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Case study: weight of evidence evaluation of the human health relevance of thiamethoxam-related mouse liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Proliferating cell nuclear antigen (PCNA): ringmaster of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

An international Ki67 reproducibility study

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

DNA reactivity as a mode of action and its relevance to cancer risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Multiple roles of the proliferating cell nuclear antigen: DNA replication, repair and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

The Ki-67 protein: from the known and the unknown

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Factors predicting late recurrence for estrogen receptor-positive breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.

21 January 2018

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IPCS conceptual framework for evaluating a mode of action for chemical carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1177%2F0192623315576005

Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Long-term feeding of sodium saccharin to nonhuman primates: implications for urinary tract cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Accurate determination of S-phase fraction in proliferative cells by dual fluorescence and peroxidase immunohistochemistry with 5-bromo-2'-deoxyuridine (BrdU) and Ki67 antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Improving the human hazard characterization of chemicals: a Tox21 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Proliferation marker Ki-67 in early breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Accurate quantitation of Ki67-positive proliferating hepatocytes in rabbit liver by a multicolor immunohistochemical (IHC) approach analyzed with automated tissue and cell segmentation software

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Artificial sweeteners--do they bear a carcinogenic risk?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Carcinogen testing: current problems and new approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Comparative time course profiles of phthalate stereoisomers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Loss of histone deacetylases 1 and 2 in hepatocytes impairs murine liver regeneration through Ki67 depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Human hepatocytes support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogen sodium phenobarbital in an in vivo study using a chimeric mouse with humanized liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0192623315576005

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

21 January 2018

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/ETC.34

12 June 2024

Identifiers

DOI

10.1177/0192623315576005

1 reference

27 June 2017

1 reference