(Q31041215)

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The acquisition and application of absorption, distribution, metabolism, and excretion (ADME) data in agricultural chemical safety assessments

scientific article

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scholarly article

1 reference

Europe PubMed Central

28 June 2017

1 reference

Europe PubMed Central

The acquisition and application of absorption, distribution, metabolism, and excretion (ADME) data in agricultural chemical safety assessments (English)

1 reference

Europe PubMed Central

28 June 2017

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Janice Elaine Chambers

4

object named as

Janice E Chambers

1 reference

Europe PubMed Central

28 June 2017

Janet J. Diliberto

5

object named as

Janet Diliberto

1 reference

Europe PubMed Central

28 June 2017

author name string

Hugh A Barton

1

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Europe PubMed Central

28 June 2017

Timothy P Pastoor

2

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Europe PubMed Central

28 June 2017

Karl Baetcke

3

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Europe PubMed Central

28 June 2017

Nancy G Doerrer

6

1 reference

Europe PubMed Central

28 June 2017

Jeffrey H Driver

7

1 reference

Europe PubMed Central

28 June 2017

Charles E Hastings

8

1 reference

Europe PubMed Central

28 June 2017

Seshadri Iyengar

9

1 reference

Europe PubMed Central

28 June 2017

Robert Krieger

10

1 reference

Europe PubMed Central

28 June 2017

Bernhard Stahl

11

1 reference

Europe PubMed Central

28 June 2017

Charles Timchalk

12

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Europe PubMed Central

28 June 2017

language of work or name

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publication date

1 January 2006

1 reference

Europe PubMed Central

28 June 2017

Critical Reviews in Toxicology

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Europe PubMed Central

28 June 2017

36

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Europe PubMed Central

28 June 2017

1

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Europe PubMed Central

28 June 2017

9-35

1 reference

Europe PubMed Central

28 June 2017

Computational pharmacokinetics during developmental windows of susceptibility

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An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

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Dose-dependent metabolism and dose setting in chronic studies

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Agricultural chemical safety assessment: A multisector approach to the modernization of human safety requirements.

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Incorporating biological information in quantitative risk assessment: an example with methylene chloride

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Review and evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry

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A tiered approach to life stages testing for agricultural chemical safety assessment

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Evaluation of Physiologically Based Models of Pregnancy and Lactation for Their Application in Children's Health Risk Assessments

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Principles underlying dose selection for, and extrapolation from, the carcinogen bioassay: dose influences mechanism

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A tiered approach to systemic toxicity testing for agricultural chemical safety assessment

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Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

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Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).

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Enterohepatic circulation of indomethacin and its role in intestinal irritation

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The use of pharmacokinetics as an interpretive and predictive tool in chemical toxicology testing and risk assessment: a position paper on the appropriate use of pharmacokinetics in chemical toxicology

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An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.

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Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation

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Gender differences in pharmacokinetics

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Computer systems for the prediction of toxicity: an update

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Effects of rat alpha-fetoprotein administration on estradiol free fraction, the onset of puberty, and neural and uterine nuclear estrogen receptors

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The significance of plasma protein binding on the fetal/maternal distribution of drugs at steady-state

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In vitro human phase I metabolism of xenobiotics I: pesticides and related compounds used in agriculture and public health, May 2003

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A Bayesian analysis of the influence of GSTT1 polymorphism on the cancer risk estimate for dichloromethane.

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Pesticide exposure assessment

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Risk assessments in the pesticide regulatory process

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Incorporating mechanistic data into risk assessment

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The roles of transporters and enzymes in hepatic drug processing

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Disposition and metabolic fate of atomoxetine hydrochloride: pharmacokinetics, metabolism, and excretion in the Fischer 344 rat and beagle dog.

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Lack of differential sensitivity to cholinesterase inhibition in fetuses and neonates compared to dams treated perinatally with chlorpyrifos.

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Chronokinetics of active biliary ampicillin secretion in rats.

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21 January 2018

Metabolism of bisphenol a in primary cultured hepatocytes from mice, rats, and humans

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A physiologically based model for gastrointestinal absorption and excretion of chemicals carried by lipids.

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21 January 2018

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems

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21 January 2018

Absorption, metabolism, and excretion of N,N-diethyl-m-toluamide following dermal application to human volunteers

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21 January 2018

Correlation of paraquat toxicity with tissue concentrations and weight loss of the rat

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21 January 2018

Correlation of environmental carbaryl measurements with serum and urinary 1-naphthol measurements in a farmer applicator and his family

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21 January 2018

Dose-dependent transitions in mechanisms of toxicity

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Dose-dependent transitions in mechanisms of toxicity: case studies

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Dermal penetration and potential for placental transfer of the insect repellent, N,N-diethyl-m-toluamide.

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Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile disposition in humans

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Computational modeling of serum-binding proteins and clearance in extrapolations across life stages and species for endocrine active compounds

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Estimation of dermal absorption using the exponential saturation model

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Comparative inter-species pharmacokinetics of phenoxyacetic acid herbicides and related organic acids. evidence that the dog is not a relevant species for evaluation of human health risk

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Pharmacokinetics and metabolism of triclopyr 3,5,6-trichloro-2-pyridinyloxyacetic acid) in Fischer 344 rats

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A Physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans

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Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model

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Comparative metabolism of 2,4-dichlorophenoxyacetic acid (2,4-D) in rat and dog.

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Nonlinear pharmacokinetics of hepatobiliary transport of rose bengal in rats after i.v. bolus administration with varying doses

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In vivo and in vitro percutaneous absorption and skin evaporation of isofenphos in man.

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A tiered approach to pharmacokinetic studies

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Biological monitoring for pesticide absorption.

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Interspecies comparison of the oral absorption of itraconazole in laboratory animals

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Transplacental and lactational transfer of p,p'-DDE in Sprague-Dawley rats.

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A modeling framework for estimating children's residential exposure and dose to chlorpyrifos via dermal residue contact and nondietary ingestion

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10.1080/10408440500534362

1 reference

Europe PubMed Central

28 June 2017

1 reference

Europe PubMed Central

28 June 2017

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