(Q31096798)

28 June 2017

1 reference

title

Cytochrome P450 enzymes in the generation of commercial products (English)

1 reference

28 June 2017

F Peter Guengerich

1

1 reference

28 June 2017

publication date

1 May 2002

1 reference

Nature Reviews Drug Discovery

28 June 2017

published in

1 reference

28 June 2017

volume

1

1 reference

28 June 2017

issue

5

1 reference

28 June 2017

page(s)

359-366

1 reference

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

28 June 2017

cites work

1 reference

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

21 January 2018

1 reference

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

21 January 2018

1 reference

Microbiological Transformations of Steroids.1I. Introduction of Oxygen at Carbon-11 of Progesterone

21 January 2018

1 reference

Purification and reconstitution of the electron transport components for 6-deoxyerythronolide B hydroxylase, a cytochrome P-450 enzyme of macrolide antibiotic (erythromycin) biosynthesis

21 January 2018

1 reference

Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase

21 January 2018

1 reference

Tetracenomycin F1 monooxygenase: oxidation of a naphthacenone to a naphthacenequinone in the biosynthesis of tetracenomycin C in Streptomyces glaucescens

21 January 2018

1 reference

Directed evolution of single proteins, metabolic pathways, and viruses

21 January 2018

1 reference

Directed Evolution and Biocatalysis

21 January 2018

1 reference

Molecular breeding of carotenoid biosynthetic pathways

21 January 2018

1 reference

Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase

21 January 2018

1 reference

Taxol: biosynthesis, molecular genetics, and biotechnological applications

21 January 2018

1 reference

The role of cytochrome P450 monooxygenases in plant-insect interactions

21 January 2018

1 reference

P450 inhibitors of use in medical treatment: focus on mechanisms of action

21 January 2018

1 reference

Interaction of citrus juices with felodipine and nifedipine

21 January 2018

1 reference

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

21 January 2018

1 reference

Dopamine formation from tyramine by CYP2D6.

21 January 2018

1 reference

Trichloroethylene oxidation by toluene dioxygenase

21 January 2018

1 reference

Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450(cam)).

21 January 2018

1 reference

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

21 January 2018

1 reference

Cytochrome P450 proteins and potential utilization in biodegradation

21 January 2018

1 reference

Oxidation of indole by cytochrome P450 enzymes

21 January 2018

1 reference

Rational evolution of a medium chain-specific cytochrome P-450 BM-3 variant.

21 January 2018

1 reference

Biogenesis of volatile aldehydes from fatty acid hydroperoxides: molecular cloning of a hydroperoxide lyase (CYP74C) with specificity for both the 9- and 13-hydroperoxides of linoleic and linolenic acids

21 January 2018

1 reference

Expression of Naphthalene Oxidation Genes in Escherichia coli Results in the Biosynthesis of Indigo

21 January 2018

1 reference

Construction of metabolic operons catalyzing the de novo biosynthesis of indigo in Escherichia coli.

21 January 2018

1 reference

Biotechnology, bioremediation, and blue genes.

21 January 2018

1 reference

Aromatic dioxygenases: molecular biocatalysis and applications

21 January 2018

1 reference

Formation of indigo by recombinant mammalian cytochrome P450.

21 January 2018

1 reference

Random mutagenesis of human cytochrome p450 2A6 and screening with indole oxidation products

21 January 2018

1 reference

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

21 January 2018

1 reference

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

21 January 2018

1 reference

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

21 January 2018

1 reference

Cloning and expression of cytochrome P450 genes controlling flower colour

21 January 2018

1 reference

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli

21 January 2018

1 reference

Drug metabolism by Escherichia coli expressing human cytochromes P450.

21 January 2018

1 reference

New applications of bacterial systems to problems in toxicology.

21 January 2018

1 reference

Engineering the CYP101 system for in vivo oxidation of unnatural substrates.

21 January 2018

1 reference

Discovery of superior enzymes by directed molecular evolution

21 January 2018

1 reference

Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties

21 January 2018

1 reference

Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

21 January 2018

1 reference

Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

21 January 2018

1 reference

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

21 January 2018

1 reference

Hybrid cytochromes P-450 identify a substrate binding domain in P-450IIC5 and P-450IIC4.

21 January 2018

1 reference

Directed enzyme evolution

21 January 2018

1 reference

The use of 'electronic nose' sensor responses to predict the inhibition activity of alcohols on the cytochrome P-450 catalyzed p-hydroxylation of aniline

21 January 2018

1 reference

Construction and characterization of bioelectrocatalytic sensors based on cytochromes P450.

21 January 2018

1 reference

Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus

21 January 2018

1 reference

Crystallization and preliminary X-ray diffraction analysis of a cytochrome P450 (CYP119) from Sulfolobus solfataricus

21 January 2018

1 reference

Genetically modified plants and human health risks: Can additional research reduce uncertainties and increase public confidence?

21 January 2018

1 reference

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

21 January 2018

1 reference

Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B)

21 January 2018

1 reference

Substrate specificity of 6-deoxyerythronolide B hydroxylase, a bacterial cytochrome P450 of erythromycin A biosynthesis

21 January 2018

1 reference

Aromatase inhibitors in the treatment of breast cancer

21 January 2018

1 reference

Oxidation of persistent environmental pollutants by a white rot fungus

21 January 2018

1 reference

Reductive dehalogenation by cytochrome P450CAM: substrate binding and catalysis

21 January 2018

1 reference

Enzyme-catalyzed dehalogenation of pentachloroethane: why F87W-cytochrome P450cam is faster than wild type

21 January 2018

1 reference

Directed evolution of the fatty-acid hydroxylase P450 BM-3 into an indole-hydroxylating catalyst

21 January 2018

1 reference

The great diversity of reactions catalyzed by cytochromes P450

21 January 2018

1 reference

Engineering cytochrome P-450cam to increase the stereospecificity and coupling of aliphatic hydroxylation

21 January 2018

1 reference

The use of random chimeragenesis to study structure/function properties of rat and human P450c17

21 January 2018

1 reference

Cytochrome P450 1B1: a target for inhibition in anticarcinogenesis strategies

21 January 2018

1 reference

Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase

31 March 2020

1 reference

Butane and propane oxidation by engineered cytochrome P450cam.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD792

1 reference

Dimensions Publication ID

28 June 2017

1006979163

0 references

1 reference