(Q31111648)

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Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines

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scholarly article

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Europe PubMed Central

PMC publication ID

17 October 2017

Induction of p16(INK4a) is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into lymphoblastoid cell lines (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Epstein–Barr virus

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Alison Sinclair

5

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

object named as

Kostas Paschos

6

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object named as

Robert E White

2

0 references

object named as

Ernest Turro

4

0 references

Martin J Allday

7

object named as

Martin J Allday

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Gillian A Parker

3

object named as

Gillian A Parker

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

author name string

Lenka Skalska

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

publication date

21 February 2013

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

e1003187

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

copyright license

Creative Commons Attribution 4.0 International

21 February 2013

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April 2022 Public Data File from Crossref

copyright status

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Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: implications for virus biology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV

1 reference

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E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells.

1 reference

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EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors

1 reference

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Downregulation of integrin receptor-signaling genes by Epstein-Barr virus EBNA 3C via promoter-proximal and -distal binding elements

1 reference

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The p53 network: cellular and systemic DNA damage responses in aging and cancer

1 reference

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Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis

1 reference

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21 June 2018

Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression

1 reference

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EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5

1 reference

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Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines

1 reference

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An ATM/Chk2-mediated DNA damage-responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells

1 reference

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Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification

1 reference

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Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health

1 reference

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Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.

1 reference

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21 June 2018

Epigenetic repression of p16(INK4A) by latent Epstein-Barr virus requires the interaction of EBNA3A and EBNA3C with CtBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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MMBGX: a method for estimating expression at the isoform level and detecting differential splicing using whole-transcript Affymetrix arrays

1 reference

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Polycomb group proteins: navigators of lineage pathways led astray in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Mechanisms of polycomb gene silencing: knowns and unknowns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

The Ink4/Arf locus is a barrier for iPS cell reprogramming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Differential gene expression patterns of EBV infected EBNA-3A positive and negative human B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Linking DNA methylation and histone modification: patterns and paradigms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein

1 reference

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X:Map: annotation and visualization of genome structure for Affymetrix exon array analysis.

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Cellular senescence in cancer and aging

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1 reference

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Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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The regulation of INK4/ARF in cancer and aging

1 reference

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21 June 2018

Epstein-Barr virus selectively deregulates DNA damage responses in normal B cells but has no detectable effect on regulation of the tumor suppressor p53.

1 reference

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21 June 2018

Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

1 reference

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1 reference

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Frequent methylation of p16INK4A/p14ARF promoters in tumorigenesis of Epstein-Barr virus transformed lymphoblastoid cell lines.

1 reference

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1 reference

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INK4a/ARF: a multifunctional tumor suppressor locus

1 reference

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The role of BH3-only proteins in the immune system

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SCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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Epstein-Barr virus: 40 years on

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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E2F target genes: unraveling the biology

1 reference

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Epstein-Barr virus nuclear antigen 3C regulates cyclin A/p27 complexes and enhances cyclin A-dependent kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

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EBV-encoded EBNA-5 associates with P14ARF in extranucleolar inclusions and prolongs the survival of P14ARF-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminal-binding protein (CtBP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

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Epstein-Barr virus: exploiting the immune system

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Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C

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Molecular virology of Epstein-Barr virus

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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Control of cell cycle entry and apoptosis in B lymphocytes infected by Epstein-Barr virus.

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p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-Barr virus nuclear antigen (EBNA)3C is an immortalizing oncoprotein with similar properties to adenovirus E1A and papillomavirus E7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

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Epstein-Barr virus nuclear antigen EBNA3C/6 expression maintains the level of latent membrane protein 1 in G1-arrested cells

1 reference

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21 June 2018

EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578823

21 June 2018

Epstein-Barr virus latent gene expression during the initiation of B cell immortalization

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Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

21 January 2018

p16(INK4A)-independence of Epstein-Barr virus-induced cell proliferation and virus latency

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

21 January 2018

The tumor suppressor p16Ink4a regulates T lymphocyte survival.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

21 January 2018

Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

21 January 2018

The assumptions underlying the analysis of variance.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

21 January 2018

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1003187

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Transgenic expression of the p16(INK4a) cyclin-dependent kinase inhibitor leads to enhanced apoptosis and differentiation arrest of CD4-CD8- immature thymocytes

1 reference

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12 December 2020

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10.1371/JOURNAL.PPAT.1003187

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

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