(Q31150898)

English

A small inhibitor of the interaction between Bax and Bcl-X(L) can synergize with methylprednisolone to induce apoptosis in Bcl-X(L)-overexpressing breast-cancer cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

A small inhibitor of the interaction between Bax and Bcl-X(L) can synergize with methylprednisolone to induce apoptosis in Bcl-X(L)-overexpressing breast-cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

1 reference

based on heuristic

inferred from title

methylprednisolone

1 reference

based on heuristic

inferred from title

author name string

Yee-Joo Tan

1

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Eileen Teng

2

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Anthony E Ting

3

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

16 July 2003

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Journal of Cancer Research and Clinical Oncology

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

129

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

437-448

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

https://scigraph.springernature.com/pub.10.1007/s00432-003-0464-4

0 references

Apoptosis: a product of programmed and unprogrammed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life-or-death decisions by the Bcl-2 protein family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense oligonucleotides: promise and reality.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of proapoptotic proteins Bax and Bcl-X(S) in p53 overexpressing hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemical biology of apoptosis. Exploring protein-protein interactions and the life and death of cells with small molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2 family: regulators of cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optical biosensors in drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Technology evaluation: G-3139.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of G3139, a phosphorothioate oligodeoxynucleotide antisense to bcl-2, after intravenous administration or continuous subcutaneous infusion to mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-ionic detergent affects the conformation of a functionally active mutant of Bcl-X(L)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticancer drug resistance and inhibition of apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BIAcore for macromolecular interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis in lung-cancer cells following bcl-xL anti-sense treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family proteins: regulators of chemoresistance in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticosteroids in the management of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemosensitization and delayed androgen-independent recurrence of prostate cancer with the use of antisense Bcl-2 oligodeoxynucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 antisense oligonucleotides (G3139) inhibit Merkel cell carcinoma growth in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of synergism or antagonism for the combined action of antiviral agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical characterization of the oligomeric state of Bax and its complex formation with Bcl-XL.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense oligonucleotides: towards clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bcl-2 gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 and the regulation of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of myeloid leukemic cells induced by high-dose methylprednisolone in patients with acute myeloblastic leukemia and its therapeutic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Megadose methylprednisolone for granulocytic sarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From bench to clinic with apoptosis-based therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the bcl-2 gene in human follicular lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family proteins as targets for anticancer drug design

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of apoptosis avoidance in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What is synergy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic-acid therapeutics: basic principles and recent applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitating oligonucleotide delivery: helping antisense deliver on its promise

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense oligonucleotides suppress B-cell lymphoma growth in a SCID-hu mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo electroporetic transfer of bcl-2 antisense oligonucleotide inhibits the development of hepatocellular carcinoma in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Choosing drug therapy for multiple sclerosis. An update.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double identity for proteins of the Bcl-2 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promise and problems of Bcl-2 antisense therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-articular corticosteroids. Guide to selection and indications for use.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2: prevention of apoptosis as a mechanism of drug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bcl-2 gene family

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of proteases during apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligonucleotide therapeutics: a step forward

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 family: life-or-death switch

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-2 in cancer, development and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced by anticancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic chemosensitization and inhibition of progression to androgen independence by antisense Bcl-2 oligodeoxynucleotide and paclitaxel in the LNCaP prostate tumor model

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/12884026

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00432-003-0464-4

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 June 2017

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