(Q31151665)

29 June 2017

title

The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity (English)

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29 June 2017

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ChEBI release 2020-05-28

5

F Ann Walker

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29 June 2017

Chiung-Kuang J Chen

1

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29 June 2017

Tatiana Kh Shokhireva

series ordinal

2

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29 June 2017

Robert E Berry

series ordinal

3

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29 June 2017

Hongjun Zhang

series ordinal

4

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29 June 2017

publication date

8 April 2008

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Journal of Biological Inorganic Chemistry

29 June 2017

published in

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29 June 2017

volume

13

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29 June 2017

issue

5

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29 June 2017

page(s)

813-824

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Electron transfer by diflavin reductases.

29 June 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00775-008-0368-5

Protein engineering of cytochromes P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0368-5

Rational evolution of a medium chain-specific cytochrome P-450 BM-3 variant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0368-5

Structure-function analysis of cytochromes P450 2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0368-5

Fatty acid metabolism, conformational change, and electron transfer in cytochrome P-450(BM-3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00775-008-0368-5

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

21 January 2018

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12 December 2020

Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase

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12 December 2020

The role of Thr268 in oxygen activation of cytochrome P450BM-3

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12 December 2020

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES

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12 December 2020

NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam.

1 reference

12 December 2020

A Single Mutation in Cytochrome P450 BM3 Changes Substrate Orientation in a Catalytic Intermediate and the Regiospecificity of Hydroxylation†

1 reference

12 December 2020

Identification of unique amino acids that modulate CYP4A7 activity

1 reference

12 December 2020

Engineering new functions and altering existing functions

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12 December 2020

Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450.

1 reference

12 December 2020

Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide

1 reference

12 December 2020

Engineering human cytochrome P450 enzymes into catalytically self-sufficient chimeras using molecular Lego.

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12 December 2020

How enzymes adapt: lessons from directed evolution

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12 December 2020

The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction

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12 December 2020

Farnesol and farnesal dehydrogenase(s) in corpora allata of the tobacco hornworm moth, Manduca sexta

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12 December 2020

Regio- and stereoselectivity of diethylaluminum azide opening of trisubstituted epoxides and conversion of the 3 degrees azidohydrin adducts to isoprenoid aziridines

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12 December 2020

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences

1 reference

12 December 2020

Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons

1 reference

12 December 2020

Functional characterisation of an engineered multidomain human P450 2E1 by molecular Lego.

1 reference

12 December 2020

Engineering mammalian cytochrome P450 2B1 by directed evolution for enhanced catalytic tolerance to temperature and dimethyl sulfoxide.

1 reference

12 December 2020

P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation

1 reference

12 December 2020

Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7.

1 reference

12 December 2020

A PCR-based strategy for extensive mutagenesis of a target DNA sequence

1 reference

12 December 2020

Assessment of protein models with three-dimensional profiles

1 reference

12 December 2020

Fatty acid monooxygenation by P450BM-3: Product identification and proposed mechanisms for the sequential hydroxylation reactions

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12 December 2020

Effective protein sequence comparison

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12 December 2020

Critical residues involved in FMN binding and catalytic activity in cytochrome P450BM-3.

1 reference

12 December 2020

A cytochrome P450 terpenoid hydroxylase linked to the suppression of insect juvenile hormone synthesis

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12 December 2020

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

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12 December 2020

Apis mellifera ultraspiracle: cDNA sequence and rapid up-regulation by juvenile hormone.

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12 December 2020

Molecular Lego: design of molecular assemblies of P450 enzymes for nanobiotechnology

1 reference

12 December 2020

Engineering of cytochrome P450 3A4 for enhanced peroxide-mediated substrate oxidation using directed evolution and site-directed mutagenesis.

1 reference

12 December 2020

Modeling protein-substrate interactions in the heme domain of cytochrome P450(BM-3).

1 reference

12 December 2020

Structure of a cytochrome P450-redox partner electron-transfer complex

1 reference

12 December 2020

Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes

1 reference

12 December 2020

Directed evolution of the fatty-acid hydroxylase P450 BM-3 into an indole-hydroxylating catalyst

1 reference

12 December 2020

CYP15A1, the cytochrome P450 that catalyzes epoxidation of methyl farnesoate to juvenile hormone III in cockroach corpora allata.

1 reference

12 December 2020

Structural determinants of active site binding affinity and metabolism by cytochrome P450 BM-3.

1 reference

12 December 2020

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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12 December 2020

Pivotal role of water in the mechanism of P450BM-3

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12 December 2020

Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain.

1 reference

12 December 2020

Roles of key active-site residues in flavocytochrome P450 BM3

1 reference

12 December 2020

Purification of bacterial cytochrome P-450

1 reference

12 December 2020

An active site substitution, F87V, converts cytochrome P450 BM-3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase

1 reference

12 December 2020

Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450 BM-3

1 reference

12 December 2020

Use of directed evolution of mammalian cytochromes P450 for investigating the molecular basis of enzyme function and generating novel biocatalysts

1 reference

12 December 2020

The highly stereoselective oxidation of polyunsaturated fatty acids by cytochrome P450BM-3

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12 December 2020

The interaction of cytochrome c and the heme domain of cytochrome P-450BM-3 with the reductase domain of cytochrome P-450BM-3

1 reference

12 December 2020

Assessing protein structures with a non-local atomic interaction energy.

1 reference

12 December 2020

Micromolar protein concentrations and metalloprotein stoichiometries obtained by inductively coupled plasma atomic emission spectrometric determination of sulfur

1 reference

12 December 2020

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

1 reference

12 December 2020

Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide

1 reference

12 December 2020

P450 BM3: the very model of a modern flavocytochrome

1 reference

12 December 2020

Thermostabilization of a cytochrome p450 peroxygenase.

1 reference

12 December 2020

Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3.

1 reference

12 December 2020

Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.

1 reference

12 December 2020

Characterization of a catalytically self-sufficient 119,000-dalton cytochrome P-450 monooxygenase induced by barbiturates in Bacillus megaterium.

1 reference

12 December 2020

Omega-1, Omega-2 and Omega-3 hydroxylation of long-chain fatty acids, amides and alcohols by a soluble enzyme system from Bacillus megaterium

1 reference

12 December 2020

10.1007/S00775-008-0368-5

Identifiers

DOI

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Dimensions Publication ID

29 June 2017

1001944414

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