(Q33160342)

23 July 2017

title

Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG. (English)

1 reference

23 July 2017

main subject

protein ubiquitination

1 reference

Adrienne T Dennis

1

1 reference

23 July 2017

Drew Nassal

2

1 reference

23 July 2017

Isabelle Deschenes

3

1 reference

23 July 2017

Dierk Thomas

4

1 reference

23 July 2017

Eckhard Ficker

5

1 reference

23 July 2017

language of work or name

English

0 references

publication date

9 August 2011

1 reference

23 July 2017

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

23 July 2017

volume

286

1 reference

23 July 2017

issue

39

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23 July 2017

page(s)

34413-34425

1 reference

β-arrestin-biased signaling by the β-adrenergic receptors

23 July 2017

cites work

1 reference

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21 June 2018

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Local clustering of transferrin receptors promotes clathrin-coated pit initiation.

21 June 2018

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The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions

21 June 2018

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21 June 2018

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21 June 2018

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Involvement of caveolin in low K+-induced endocytic degradation of cell-surface human ether-a-go-go-related gene (hERG) channels

21 June 2018

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Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

21 June 2018

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21 June 2018

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21 June 2018

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Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition

21 June 2018

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Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines

21 June 2018

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21 June 2018

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21 June 2018

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Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells

21 June 2018

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21 June 2018

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Internalized Kv1.5 traffics via Rab-dependent pathways

21 June 2018

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Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol

21 June 2018

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Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis

21 June 2018

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Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome

21 June 2018

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hERG channel trafficking: novel targets in drug-induced long QT syndrome

21 June 2018

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Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

21 June 2018

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Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels.

21 June 2018

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hERG potassium channels and cardiac arrhythmia

21 June 2018

1 reference

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Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor

21 June 2018

1 reference

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HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk

21 June 2018

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Pentamidine reduces hERG expression to prolong the QT interval

21 June 2018

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Pharmacologic treatment of binge eating disorder

21 June 2018

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Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.

21 June 2018

1 reference

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Psychotropic drugs, cardiac arrhythmia, and sudden death

21 June 2018

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The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

21 June 2018

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21 June 2018

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Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190784

Death of two subjects due to imipramine and desipramine metabolite accumulation during chronic therapy: a review of the literature and possible mechanisms.

21 June 2018

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Calmodulin regulates endosome fusion

21 June 2018

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The calmodulin antagonist, W-13, alters transcytosis, recycling, and the morphology of the endocytic pathway in Madin-Darby canine kidney cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190784

Tricyclic medication in children and the QT interval: case report and discussion

21 June 2018

1 reference

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Evidence for lysosomotropic action of desipramine in cultured human fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190784

Torsade de pointes caused by tricyclic antidepressive agents. Description of a clinical case

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190784

Measurement of free desipramine in serum by ultrafiltration with immunoassay

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3190784

Mechanisms of arsenic-induced prolongation of cardiac repolarization

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Pentamidine-induced long QT syndrome and block of hERG trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Cyclic antidepressants and the risk of sudden cardiac death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Rab-GTPase-dependent endocytic recycling of Kv1.5 in atrial myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.254367

Use of cyclodextrins for manipulating cellular cholesterol content

21 January 2018

1 reference

12 December 2020

Isolation and characterization of I(Kr) in cardiac myocytes by Cs+ permeation

1 reference

12 December 2020

Cardiovascular effects of desipramine in children and adults during exercise testing

1 reference

12 December 2020

Electrocardiographic changes during desipramine and clomipramine treatment in children and adolescents

1 reference

12 December 2020

Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships

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12 December 2020

Identifiers

DOI

10.1074/JBC.M111.254367

1 reference

23 July 2017

1 reference

23 July 2017

1 reference