(Q33195487)

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Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Induction of apoptosis by enediyne antibiotic calicheamicin thetaII proceeds through a caspase-mediated mitochondrial amplification loop in an entirely Bax-dependent manner (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

author name string

Aram Prokop

1

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Wolf Wrasidlo

2

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Holger Lode

3

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Ralf Herold

4

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Florian Lang

5

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Günter Henze

6

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Bernd Dörken

7

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Thomas Wieder

8

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Peter T Daniel

9

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

language of work or name

0 references

publication date

1 December 2003

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

57

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

9107-9120

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biology

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Calicheamicins, a novel family of antitumor antibiotics: taxonomy, fermentation and biological properties

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Cyclin D3 activates Caspase 2, connecting cell proliferation with cell death

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Cell-specific regulation of apoptosis by designed enediynes

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A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

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Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine

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Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

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Caspases: the executioners of apoptosis

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Dissecting the pathways to death

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Guardians of cell death: the Bcl-2 family proteins

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Detection of genomic DNA fragmentation during apoptosis (DNA ladder) and the simultaneous isolation of RNA from low cell numbers

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Molecular remission of Philadelphia/bcr-abl-positive acute myeloid leukaemia after treatment with anti-CD33 calicheamicin conjugate (gemtuzumab ozogamicin, CMA-676)

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Recent insights into the mechanism of glucocorticosteroid-induced apoptosis

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Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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If phosphatidylserine is the death knell, a new phosphatidylserine-specific receptor is the bellringer

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Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

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Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

1 reference

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Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

1 reference

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Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis

1 reference

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Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

1 reference

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Regulation of apoptosis in leukemic cells by analogs of dynemicin A

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Origin and evolution of eukaryotic apoptosis: the bacterial connection

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Mitochondrial control of cell death

1 reference

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Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

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Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability

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Early phase I/II trials with gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia.

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Synthetic calicheamicin mimics with novel initiation mechanisms: DNA cleavage, cytotoxicity, and apoptosis

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Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

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The apoptosis promoting Bcl-2 homologues Bak and Nbk/Bik overcome drug resistance in Mdr-1-negative and Mdr-1-overexpressing breast cancer cell lines

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1 reference

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1 reference

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DNA bending is a determinant of calicheamicin target recognition

1 reference

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1 reference

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1 reference

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Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential

1 reference

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1 reference

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1 reference

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1 reference

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based on heuristic

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

1 reference

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7 January 2021

based on heuristic

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues.

1 reference

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based on heuristic

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1 reference

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based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207196

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 July 2017

ResearchGate publication ID

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