(Q33250260)

24 July 2017

title

Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation (English)

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24 July 2017

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4

Denise Harhausen

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Peter A. Ward

11

object named as

Peter A Ward

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24 July 2017

9

Markus Huber-Lang

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24 July 2017

8

Daniel Rittirsch

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24 July 2017

2

V Michael Holers

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24 July 2017

12

Philip F Stahel

1 reference

24 July 2017

Iris Leinhase

1

1 reference

24 July 2017

Joshua M Thurman

3

1 reference

24 July 2017

Denise Harhausen

4

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24 July 2017

Oliver I Schmidt

5

1 reference

24 July 2017

Malte Pietzcker

6

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24 July 2017

Mohy E Taha

7

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24 July 2017

Wade R Smith

10

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24 July 2017

publication date

14 July 2006

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24 July 2017

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24 July 2017

volume

7

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24 July 2017

page(s)

55

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The role of the complement system in CNS inflammatory diseases

24 July 2017

cites work

1 reference

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Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis

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21 June 2018

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CD46 plays a key role in tailoring innate immune recognition of apoptotic and necrotic cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist.

21 June 2018

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21 June 2018

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Moderate and severe traumatic brain injury: epidemiologic, imaging and neuropathologic perspectives

21 June 2018

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The alternative pathway of complement in disease: opportunities for therapeutic targeting

21 June 2018

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21 June 2018

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Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice

21 June 2018

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Temporal alterations in cellular Bax:Bcl-2 ratio following traumatic brain injury in the rat

21 June 2018

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Apoptosis and caspases in neurodegenerative diseases

21 June 2018

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Beyond lysis: how complement influences cell fate.

21 June 2018

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Neuronal expression of a functional receptor for the C5a complement activation fragment

21 June 2018

1 reference

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Caspase pathways, neuronal apoptosis, and CNS injury

21 June 2018

1 reference

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Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis

21 June 2018

1 reference

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Gender differences in acute CNS trauma and stroke: neuroprotective effects of estrogen and progesterone

21 June 2018

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Inhibition of complement as a therapeutic approach in inflammatory central nervous system (CNS) disease

21 June 2018

1 reference

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Complement anaphylatoxin receptors on neurons: new tricks for old receptors?

21 June 2018

1 reference

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Regulation of the complement membrane attack pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

A neuronal C5a receptor and an associated apoptotic signal transduction pathway

21 June 2018

1 reference

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Abrogation of the alternative complement pathway by targeted deletion of murine factor B

21 June 2018

1 reference

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TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis

21 June 2018

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An experimental model of closed head injury in mice: pathophysiology, histopathology, and cognitive deficits

21 June 2018

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Expression of complement in the brain: role in health and disease

21 June 2018

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Pharmacological complement inhibition at the C3 convertase level promotes neuronal survival, neuroprotective intracerebral gene expression, and neurological outcome after traumatic brain injury

21 June 2018

1 reference

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Administration of vaccinia virus complement control protein shows significant cognitive improvement in a mild injury model

31 October 2018

1 reference

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Complement-dependent apoptosis and inflammatory gene changes in murine lupus cerebritis

31 October 2018

1 reference

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Complement activation after lumbosacral ventral root avulsion injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury.

31 October 2018

1 reference

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Complement activation following optic nerve crush in the adult rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Intracerebroventricular injection of the terminal complement complex causes inflammatory reaction in the rat brain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Pathways leading to apoptotic neurodegeneration following trauma to the developing rat brain

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Vaccinia virus complement control protein enhances functional recovery after traumatic brain injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Mild traumatic brain injury induces apoptotic cell death in the cortex that is preceded by decreases in cellular Bcl-2 immunoreactivity

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

In situ DNA fragmentation occurs in white matter up to 12 months after head injury in man.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Enhanced glial activation and expression of specific CNS inflammation-related molecules in aged versus young rats following cortical stab injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Intrathecal levels of complement-derived soluble membrane attack complex (sC5b-9) correlate with blood-brain barrier dysfunction in patients with traumatic brain injury.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

BCL-2 overexpression attenuates cortical cell loss after traumatic brain injury in transgenic mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Elevated levels of the complement components C3 and factor B in ventricular cerebrospinal fluid of patients with traumatic brain injury

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Activation of the complement cascade and increase of clusterin in the brain following a cortical contusion in the adult rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Evidence of apoptotic cell death after experimental traumatic brain injury in the rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1540436

Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury

31 October 2018

1 reference

12 December 2020

Complement activation in the human brain after traumatic head injury

1 reference

12 December 2020

Acute tubular necrosis is characterized by activation of the alternative pathway of complement

1 reference

12 December 2020

Local neutrophil influx following lateral fluid-percussion brain injury in rats is associated with accumulation of complement activation fragments of the third component (C3) of the complement system

1 reference

12 December 2020

The role of the complement system in traumatic brain injury

1 reference

12 December 2020

Attenuation of experimental autoimmune demyelination in complement-deficient mice

1 reference

12 December 2020

Effect of Soluble Complement Receptor-1 on Neutrophil Accumulation after Traumatic Brain Injury in Rats

1 reference

12 December 2020

Generation of C5a in the absence of C3: a new complement activation pathway

1 reference

12 December 2020

A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice

1 reference

12 December 2020

Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in mice

1 reference

12 December 2020

Neutrophil dysfunction in sepsis. II. Evidence for the role of complement activation products in cellular deactivation

1 reference

12 December 2020

Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines

1 reference

12 December 2020

Closed head injury--an inflammatory disease?

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2202-7-55

1 reference

Dimensions Publication ID

24 July 2017

0 references

1 reference

24 July 2017

1 reference