(Q33286495)

25 July 2017

title

Presenilin-1 C410Y Alzheimer disease plaques contain synaptic proteins (English)

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25 July 2017

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Kamran Haleem

1

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25 July 2017

Carol F Lippa

2

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25 July 2017

Thomas W Smith

3

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25 July 2017

Hisatomo Kowa

4

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25 July 2017

Jianlin Wu

5

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25 July 2017

Takeshi Iwatsubo

6

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25 July 2017

language of work or name

English

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publication date

1 April 2007

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American Journal of Alzheimer's Disease & Other Dementias

25 July 2017

published in

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25 July 2017

volume

22

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25 July 2017

issue

2

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25 July 2017

page(s)

137-144

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Alzheimer Disease in the US Population

25 July 2017

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21 January 2018

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Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

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Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

21 January 2018

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21 January 2018

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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

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21 January 2018

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21 January 2018

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Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

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Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

21 January 2018

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A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease.

21 January 2018

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Notch1 and its ligands Delta-like and Jagged are expressed and active in distinct cell populations in the postnatal mouse brain.

21 January 2018

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Notch1 inhibits neurite outgrowth in postmitotic primary neurons

21 January 2018

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Involvement of Notch signaling in hippocampal synaptic plasticity

21 January 2018

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Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1177/1533317506298051

1 reference

release_472ijw7ypzallnh7sqeuj7f7bu

25 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/472ijw7ypzallnh7sqeuj7f7bu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference