(Q33287254)

25 July 2017

title

Potency of a tau fibrillization inhibitor is influenced by its aggregation state (English)

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25 July 2017

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Erin E Congdon

1

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25 July 2017

Mihaela Necula

series ordinal

2

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25 July 2017

Robert D Blackstone

series ordinal

3

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25 July 2017

Jeff Kuret

series ordinal

4

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25 July 2017

language of work or name

English

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publication date

25 May 2007

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25 July 2017

number of pages

9

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Archives of Biochemistry and Biophysics

inferred from page(s)

published in

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25 July 2017

volume

465

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25 July 2017

issue

1

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25 July 2017

page(s)

127-135

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THE MECHANISM OF ENZYME-INHIBITOR-SUBSTRATE REACTIONS : ILLUSTRATED BY THE CHOLINESTERASE-PHYSOSTIGMINE-ACETYLCHOLINE SYSTEM.

25 July 2017

cites work

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C-terminal truncation modulates both nucleation and extension phases of tau fibrillization

21 June 2018

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Evaluating triggers and enhancers of tau fibrillization.

21 June 2018

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Tau suppression in a neurodegenerative mouse model improves memory function

21 June 2018

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A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

21 June 2018

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The binding of thioflavin-T to amyloid fibrils: localisation and implications

21 June 2018

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Pathways of tau fibrillization.

21 June 2018

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Transcriptional and conformational changes of the tau molecule in Alzheimer's disease

21 June 2018

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Synthesis of analogues of Congo red and evaluation of their anti-prion activity

21 June 2018

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A static laser light scattering assay for surfactant-induced tau fibrillization

21 June 2018

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Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro

21 June 2018

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Template-assisted filament growth by parallel stacking of tau.

21 June 2018

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Conformational constraints for amyloid fibrillation: the importance of being unfolded

21 June 2018

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Imaging linear birefringence and dichroism in cerebral amyloid pathologies

21 June 2018

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 June 2018

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Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

21 June 2018

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Cyanines during the 1990s: A Review

21 June 2018

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Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

21 June 2018

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Screening Congo Red and its analogues for their ability to prevent the formation of PrP-res in scrapie-infected cells

21 June 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

21 June 2018

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

21 June 2018

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A high-throughput screen for aggregation-based inhibition in a large compound library

21 June 2018

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Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

31 October 2018

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Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases

31 October 2018

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Triggers of full-length tau aggregation: a role for partially folded intermediates.

31 October 2018

1 reference

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Site-specific pseudophosphorylation modulates the rate of tau filament dissociation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Electron microscopy as a quantitative method for investigating tau fibrillization

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Ligand-dependent inhibition and reversal of tau filament formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Evidence for an intermediate in tau filament formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

The structure and protein binding of amyloid-specific dye reagents.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Pinacyanol as effective probe of fibrillar β‐amyloid peptide: Comparative study with Congo Red

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Synthesis and evaluation of analogues of Congo red as potential compounds against transmissible spongiform encephalopathies

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Anionic Micelles and Vesicles Induce Tau Fibrillization in Vitro

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Protein folding and disease: a view from the first Horizon Symposium.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Is Congo red an amyloid-specific dye?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Supramolecular ligands: monomer structure and protein ligation capability.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Structural aspects of Congo red as an inhibitor of protease-resistant prion protein formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Congo red-stabilized intermediates in the lambda light chain transition from native to molten state

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2048980

Selective staining by the fluorochrome, 5,5-diphenyl-9-ethyl-DiOC2(3). I. Physicochemical studies of dye-dye and dye-tissue interactions

31 October 2018

1 reference

12 December 2020

Band-shifting through polypeptide beta-sheet structures in the cyanine UV-Vis spectrum

1 reference

12 December 2020

Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau

1 reference

12 December 2020

10.1016/J.ABB.2007.05.004

Identifiers

DOI

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25 July 2017

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25 July 2017

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