(Q33305811)

25 July 2017

title

Chemical genetic screening identifies tricyclic compounds that decrease cellular melanin content (English)

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25 July 2017

Seth J Orlow

2

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author name string

Li Ni-Komatsu

series ordinal

1

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25 July 2017

language of work or name

English

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publication date

15 November 2007

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Journal of Investigative Dermatology

25 July 2017

published in

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25 July 2017

volume

128

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25 July 2017

issue

5

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25 July 2017

page(s)

1236-1247

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https://scigraph.springernature.com/pub.10.1038/sj.jid.5701163

25 July 2017

exact match

0 references

cites work

Acute effects of two melanocytolytic agents, hydroquinone and β-mercaptoethanolamine, upon tyrosinase activity and cyclic nucleotide levels in murine melanomas

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7 January 2021

A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature.

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7 January 2021

Chemical and instrumental approaches to treat hyperpigmentation

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7 January 2021

Antidepressant-induced switch of beta 1-adrenoceptor trafficking as a mechanism for drug action

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Pink-eyed dilution protein controls the processing of tyrosinase.

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4.

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Inhibitors of mammalian melanocyte tyrosinase: in vitro comparisons of alkyl esters of gentisic acid with other putative inhibitors

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Melanosome biogenesis: shedding light on the origin of an obscure organelle

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7 January 2021

Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells

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7 January 2021

Pharmacokinetics of doxepin in subjects with pruritic atopic dermatitis

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7 January 2021

Accumulation of tyrosinase in the endolysosomal compartment is induced by U18666A.

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7 January 2021

Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation.

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7 January 2021

Redefining the skin's pigmentary system with a novel tyrosinase assay

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Mammalian monophenol monooxygenase (tyrosinase): purification, properties, and reactions catalyzed.

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Biogenesis of pigment granules: a sensitive way to regulate melanocyte function

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Some aspects of melanin biology: 1950-1975.

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Improved tyrosinase activity stains in polyacrylamide electrophoresis gels

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Identification of the F1F0 mitochondrial ATPase as a target for modulating skin pigmentation by screening a tagged triazine library in zebrafish

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Strategies for facilitated forward chemical genetics

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future.

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7 January 2021

Interactions of acid sphingomyelinase and lipid bilayers in the presence of the tricyclic antidepressant desipramine

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7 January 2021

Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

The melanosome: membrane dynamics in black and white

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7 January 2021

Topical application of doxepin hydrochloride, capsaicin and a combination of both produces analgesia in chronic human neuropathic pain: a randomized, double-blind, placebo-controlled study

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Inhibition of melanization in human melanoma cells by a serotonin uptake inhibitor

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https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Imipramine-induced facial pigmentation: case report and literature review

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Imipramine-induced hyperpigmentation: four cases and a review of the literature.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Identification of novel pigmentation modulators by chemical genetic screening

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Melanosomes are specialized members of the lysosomal lineage of organelles.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Imipramine induced lipidosis and dexamethasone effect: morphological and biochemical study in normal and chronic GM2 gangliosidosis fibroblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Survey and mechanism of skin depigmenting and lightening agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Depigmenting Action of Hydroquinone Depends on Disruption of Fundamental Cell Processes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Normal tyrosine transport and abnormal tyrosinase routing in pink-eyed dilution melanocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Melanocytes derived from patients with Hermansky-Pudlak Syndrome types 1, 2, and 3 have distinct defects in cargo trafficking

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Accumulation of cholesterol and GM2 ganglioside in cells cultured in the presence of progesterone: an implication for the basic defect in Niemann-Pick disease type C.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Ocular albinism type 1: more than meets the eye.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Photoinduced dermal pigmentation in patients taking tricyclic antidepressants: histology, electron microscopy, and energy dispersive spectroscopy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Melanin pigmentation in mammalian skin and its hormonal regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Advances in chemical genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Dissection of melanogenesis with small molecules identifies prohibitin as a regulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Hypopigmenting agents: an updated review on biological, chemical and clinical aspects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Human and mouse disorders of pigmentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Sweet surrender to chemical genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Single and multiple desipramine exposures of cultured cells. Changes in cellular anisotropy and in lipid composition of whole cells and of plasma membranes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Promotion of tyrosinase folding in COS 7 cells by calnexin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Expression of a mouse tyrosinase cDNA in 3T3 Swiss mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

In vivo drug discovery in the zebrafish

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JID.5701163

7 January 2021

Identifiers

DOI

10.1038/SJ.JID.5701163

1 reference

Dimensions Publication ID

25 July 2017

1045454966

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1 reference