(Q35828594)

10 August 2017

1 reference

title

Strategies for facilitated forward chemical genetics (English)

1 reference

10 August 2017

Young-Tae Chang

2

0 references

Sonya M Khersonsky

series ordinal

1

object named as

Sonya M Khersonsky

1 reference

10 August 2017

publication date

1 July 2004

1 reference

10 August 2017

1 reference

10 August 2017

volume

5

1 reference

10 August 2017

issue

7

1 reference

10 August 2017

page(s)

903-908

1 reference

Chemical genetics resulting from a passion for synthetic organic chemistry.

10 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Using small molecules to study big questions in cellular microbiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Combinatorial libraries and biological discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

From protein domains to drug candidates-natural products as guiding principles in the design and synthesis of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Modern methods to produce natural-product libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

High-throughput method for the production and analysis of large natural product libraries for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Pure compound libraries; a new perspective for natural product based drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Myoseverin, a microtubule-binding molecule with novel cellular effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Discovery of estrogen sulfotransferase inhibitors from a purine library screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Identification of a novel protein regulating microtubule stability through a chemical approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Dedifferentiation of lineage-committed cells by a small molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Discovery of novel antibacterial agents active against methicillin-resistant Staphylococcus aureus from combinatorial benzopyran libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Drug discovery: a historical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Solid phase synthesis of benzylamine-derived sulfonamide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Parallel synthesis and anti-malarial activity of a sulfonamide library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Chemical genetics: ligand-based discovery of gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Genomic strategies for defining and dissecting developmental and physiological pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Biological Mechanism Profiling Using an Annotated Compound Library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

HR22C16: a potent small-molecule probe for the dynamics of cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Chemical genetics: tailoring tools for cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Cellular screening assays using fluorescence microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Small molecule developmental screens reveal the logic and timing of vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Chemical proteomics and its application to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Facilitated forward chemical genetics using a tagged triazine library and zebrafish embryo screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Quantitative chemical proteomics for identifying candidate drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Epoxide electrophiles as activity-dependent cysteine protease profiling and discovery tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Profiling the specific reactivity of the proteome with non-directed activity-based probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

Developing a strategy for activity-based detection of enzymes in a protein microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400047

21 January 2018

Identifiers

DOI

10.1002/CBIC.200400047

1 reference

10 August 2017

1 reference