(Q33350410)

26 July 2017

title

Nuclear translocation of Skp2 facilitates its destruction in response to TGFβ signaling (English)

1 reference

26 July 2017

Weijun Liu

2

0 references

author name string

Dong Hu

series ordinal

1

1 reference

26 July 2017

George Wu

series ordinal

3

1 reference

26 July 2017

Yong Wan

series ordinal

4

1 reference

26 July 2017

publication date

15 January 2011

1 reference

26 July 2017

number of pages

8

1 reference

inferred from page(s)

published in

Cell Cycle

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26 July 2017

volume

10

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26 July 2017

issue

2

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26 July 2017

page(s)

285-292

1 reference

An in vivo study of Cdh1/APC in breast cancer formation.

26 July 2017

cites work

1 reference

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Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

21 June 2018

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Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

21 June 2018

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21 June 2018

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21 June 2018

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Regulation of Skp2-p27 axis by the Cdh1/anaphase-promoting complex pathway in colorectal tumorigenesis

21 June 2018

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

21 June 2018

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To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications

21 June 2018

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Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

21 June 2018

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Cdh1-anaphase-promoting complex targets Skp2 for destruction in transforming growth factor beta-induced growth inhibition

21 June 2018

1 reference

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Experimental tests to definitively determine ubiquitylation of a substrate.

21 June 2018

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Differential expression of the F-box proteins Skp2 and Skp2B in breast cancer

21 June 2018

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21 June 2018

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Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.

21 June 2018

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Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2

21 June 2018

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Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein.

21 June 2018

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Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex

21 June 2018

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Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

21 June 2018

1 reference

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Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling.

21 June 2018

1 reference

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Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 June 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 June 2018

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Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation

21 June 2018

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Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)

21 June 2018

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Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

21 June 2018

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The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 June 2018

1 reference

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Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

21 June 2018

1 reference

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TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

21 June 2018

1 reference

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Repression of p15INK4b expression by Myc through association with Miz-1

21 June 2018

1 reference

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Nuclear targeting signal recognition: a key control point in nuclear transport?

21 June 2018

1 reference

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

Nucleocytoplasmic transport: the soluble phase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

Dissection of the APCCdh1-Skp2 cascade in breast cancer.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.10.2.14517

Genomic stability and tumour suppression by the APC/C cofactor Cdh1.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.10.2.14517

Altered expression of p27 and Skp2 proteins in prostate cancer of African-American patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048799

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

31 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.10.2.14517

Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: correlation with p27(Kip1) and proliferation index

21 January 2018

1 reference

12 December 2020

Skp2 and p27kip1 expression in melanocytic nevi and melanoma: an inverse relationship

1 reference

12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

12 December 2020

Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling

1 reference

12 December 2020

Identifiers

DOI

10.4161/CC.10.2.14517

1 reference

26 July 2017

1 reference

26 July 2017

1 reference