(Q40607119)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14676846%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

Negative regulation of SCFSkp2 ubiquitin ligase by TGF-beta signaling (English)

1 reference

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22 December 2019

4

1 reference

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22 December 2019

Xuedong Liu

5

1 reference

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22 December 2019

author name string

Wei Wang

1

1 reference

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22 December 2019

Dana Ungermannova

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14676846%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Jianpin Jin

3

1 reference

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22 December 2019

language of work or name

English

0 references

publication date

1 February 2004

1 reference

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22 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14676846%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

23

1 reference

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22 December 2019

issue

5

1 reference

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22 December 2019

page(s)

1064-1075

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14676846%20AND%20SRC:MED&resulttype=core&format=json

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

22 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Retinoic acid-mediated growth arrest requires ubiquitylation and degradation of the F-box protein Skp2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Role of the F-box protein Skp2 in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Three different binding sites of Cks1 are required for p27-ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

Signal transduction by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Breast cancer banishes p27 from nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Cyclin E in human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Protein destruction: adapting roles for Cks proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Generation of mammalian cells stably expressing multiple genes at predetermined levels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Ski/Sno and TGF-beta signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207204

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14676846%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 December 2019

1029042085

0 references

Fatcat ID

release_4ukvr2ldm5bhhpazy4sv4lc2nm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4ukvr2ldm5bhhpazy4sv4lc2nm

24 November 2022

mapped directly with Wikidata item

1 reference