(Q33358054)

26 July 2017

title

Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS (English)

1 reference

amyotrophic lateral sclerosis

26 July 2017

main subject

1 reference

Don W Cleveland

6

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author name string

Yueming Chang

1

1 reference

26 July 2017

Qiongman Kong

2

1 reference

26 July 2017

Xiu Shan

3

1 reference

26 July 2017

Guilian Tian

4

1 reference

26 July 2017

Hristelina Ilieva

5

1 reference

26 July 2017

Jeffrey D Rothstein

7

1 reference

26 July 2017

David R Borchelt

8

1 reference

26 July 2017

Philip C Wong

9

1 reference

26 July 2017

Chien-Liang Glenn Lin

10

1 reference

26 July 2017

language of work or name

English

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publication date

6 August 2008

1 reference

26 July 2017

1 reference

26 July 2017

volume

3

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26 July 2017

issue

8

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26 July 2017

page(s)

e2849

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

6 August 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Oxidized messenger RNA induces translation errors

21 June 2018

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Neuronal intermediate filaments and ALS: a new look at an old question

21 June 2018

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ALS: a disease of motor neurons and their nonneuronal neighbors

21 June 2018

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Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.

21 June 2018

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Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

21 June 2018

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21 June 2018

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Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

21 June 2018

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Vitamin E intake and risk of amyotrophic lateral sclerosis

21 June 2018

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High dose vitamin E therapy in amyotrophic lateral sclerosis as add-on therapy to riluzole: results of a placebo-controlled double-blind study

21 June 2018

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A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

21 June 2018

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Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis

21 June 2018

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Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

21 June 2018

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Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

21 June 2018

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Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP

21 June 2018

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Oxidative damage to nucleic acids photosensitized by titanium dioxide

21 June 2018

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Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis

21 June 2018

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Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

21 June 2018

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The multimolecular cascade of spinal cord injury. Studies on prostanoids, calcium, and proteinases

21 June 2018

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Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies

21 January 2018

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Redox metals and oxidative abnormalities in human prion diseases

21 January 2018

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Quantification of oxidized RNAs in Alzheimer's disease

21 January 2018

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Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Ribosome dysfunction is an early event in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

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Profiling Gene Expression Using Onto-Express

21 January 2018

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4-Hydroxynonenal, a lipid peroxidation byproduct of spinal cord injury, is cytotoxic for oligodendrocyte progenitors and inhibits their responsiveness to PDGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Mutant dynactin in motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Inhibition of Chaperone Activity Is a Shared Property of Several Cu,Zn-Superoxide Dismutase Mutants That Cause Amyotrophic Lateral Sclerosis

21 January 2018

1 reference

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Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

Focused proteomics in post-mortem human spinal cord.

21 January 2018

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Human glioma cells and undifferentiated primary astrocytes that express aberrant EAAT2 mRNA inhibit normal EAAT2 protein expression and prevent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002849

The identification and characterization of oxidized RNAs in Alzheimer's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481395

Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481395

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481395

Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481395

Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2481395

Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death

31 October 2018

1 reference

12 December 2020

Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Reduction of metallothioneins promotes the disease expression of familial amyotrophic lateral sclerosis mice in a dose-dependent manner

1 reference

12 December 2020

Peroxide-scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress

1 reference

12 December 2020

Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Myelin-associated oligodendrocytic basic protein is essential for normal arrangement of the radial component in central nervous system myelin

1 reference

12 December 2020

The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0002849

Identifiers

DOI

1 reference

26 July 2017

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26 July 2017

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