(Q33371167)

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Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 July 2017

Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

Christoph Rader

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Christoph Rader

5

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author name string

Ka Yin Kwong

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Sivasubramanian Baskar

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Hua Zhang

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Crystal L Mackall

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

16 September 2008

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Europe PubMed Central

PubMed publication ID

26 July 2017

number of pages

14

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Journal of Molecular Biology

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Europe PubMed Central

PubMed publication ID

26 July 2017

384

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Europe PubMed Central

PubMed publication ID

26 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1143-1156

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Generation and selection of rabbit antibody libraries by phage display

1 reference

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21 June 2018

E. coli expression and purification of Fab antibody fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Cancer immunosurveillance: NKG2D breaks cover

1 reference

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21 June 2018

NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy

1 reference

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21 June 2018

Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia.

1 reference

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21 June 2018

The NKG2D receptor: immunobiology and clinical implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

1 reference

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21 June 2018

Blockade of NKG2D on NKT cells prevents hepatitis and the acute immune response to hepatitis B virus

1 reference

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21 June 2018

4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy

1 reference

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21 June 2018

Promiscuity and the single receptor: NKG2D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector

1 reference

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21 June 2018

Generation of antitumor responses by genetic modification of primary human T cells with a chimeric NKG2D receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Immunobiology of human NKG2D and its ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Selecting and screening recombinant antibody libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Ultra-potent antibodies against respiratory syncytial virus: effects of binding kinetics and binding valence on viral neutralization

1 reference

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21 June 2018

The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

NK cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Engagement of NKG2D by cognate ligand or antibody alone is insufficient to mediate costimulation of human and mouse CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Large antibody display libraries for isolation of high-affinity antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Rabbit immune repertoires as sources for therapeutic monoclonal antibodies: the impact of kappa allotype-correlated variation in cysteine content on antibody libraries selected by phage display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Integrin alpha(v)beta3 targeted therapy for Kaposi's sarcoma with an in vitro evolved antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Antibody libraries in drug and target discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

An activating immunoreceptor complex formed by NKG2D and DAP10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Isolation of high affinity human antibodies directly from large synthetic repertoires.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

By-passing immunization: building high affinity human antibodies by chain shuffling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

21 June 2018

The activating immunoreceptor NKG2D and its ligands are involved in allograft transplant rejection.

1 reference

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31 October 2018

Building better magic bullets--improving unconjugated monoclonal antibody therapy for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

H60/TNT-3 fusion protein activates NK cells in vitro and improves immunotherapeutic outcome in murine syngeneic tumor models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

CD107a as a functional marker for the identification of natural killer cell activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

Detection of T-cell degranulation: CD107a and b.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

NKG2D blockade prevents autoimmune diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

Redesigning an antibody fragment for faster association with its antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659651

31 October 2018

Inhibition of NKG2D receptor function by antibody therapy attenuates transfer-induced colitis in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18809410

12 December 2020

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10.1016/J.JMB.2008.09.008

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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