(Q33399653)

26 July 2017

title

Detecting morphologically distinct oligomeric forms of alpha-synuclein (English)

1 reference

26 July 2017

1 reference

Min S Wang

3

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author name string

Sharareh Emadi

1

1 reference

26 July 2017

Srinath Kasturirangan

2

1 reference

26 July 2017

Philip Schulz

4

1 reference

26 July 2017

Michael R Sierks

5

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26 July 2017

language of work or name

English

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publication date

13 January 2009

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26 July 2017

number of pages

11

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Journal of Biological Chemistry

inferred from page(s)

published in

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26 July 2017

volume

284

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26 July 2017

issue

17

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26 July 2017

page(s)

11048-11058

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Anti-oligomeric Abeta single-chain variable domain antibody blocks Abeta-induced toxicity against human neuroblastoma cells

26 July 2017

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Formation of toxic oligomeric alpha-synuclein species in living cells

21 June 2018

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Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity

21 June 2018

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Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synuclein

21 June 2018

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A strategy for designing inhibitors of alpha-synuclein aggregation and toxicity as a novel treatment for Parkinson's disease and related disorders

21 June 2018

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Single chain variable fragments against beta-amyloid (Abeta) can inhibit Abeta aggregation and prevent abeta-induced neurotoxicity

21 June 2018

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21 June 2018

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

21 June 2018

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Phthalocyanine tetrasulfonates affect the amyloid formation and cytotoxicity of alpha-synuclein

21 June 2018

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 June 2018

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alpha-Synuclein locus triplication causes Parkinson's disease

21 June 2018

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21 June 2018

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Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson's disease

21 June 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 June 2018

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Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

21 June 2018

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Alpha-synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway

21 June 2018

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Magnesium inhibits spontaneous and iron-induced aggregation of alpha-synuclein

21 June 2018

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 June 2018

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beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

21 June 2018

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Induction of neuronal cell death by Rab5A-dependent endocytosis of alpha-synuclein

21 June 2018

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Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease

21 June 2018

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Accelerated oligomerization by Parkinson's disease linked alpha-synuclein mutants

21 June 2018

1 reference

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Yeast surface display for directed evolution of protein expression, affinity, and stability

21 June 2018

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Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

21 June 2018

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A Drosophila model of Parkinson's disease

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

21 January 2018

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Synthetic filaments assembled from C-terminally truncated alpha-synuclein

21 June 2018

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

21 June 2018

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Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

21 June 2018

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

21 June 2018

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Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

21 June 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 June 2018

1 reference

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

Differentiation and survival influences of growth factors in human neuroblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

Improved oligonucleotide site-directed mutagenesis using M13 vectors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 June 2018

1 reference

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By-passing immunization. Human antibodies from V-gene libraries displayed on phage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

21 June 2018

1 reference

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Clinical and quantitative pathologic correlates of dementia with Lewy bodies

21 June 2018

1 reference

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Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

21 January 2018

1 reference

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Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Annular alpha-synuclein protofibrils are produced when spherical protofibrils are incubated in solution or bound to brain-derived membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

The plasma alpha-synuclein levels in patients with Parkinson's disease and multiple system atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Toxicity of non-abeta component of Alzheimer's disease amyloid, and N-terminal fragments thereof, correlates to formation of beta-sheet structure and fibrils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

A single-chain Fv intrabody provides functional protection against the effects of mutant protein in an organotypic slice culture model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M806559200

Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806559200

In vitro preparation of prefibrillar intermediates of amyloid-beta and alpha-synuclein.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

Neurodegenerative disease: amyloid pores from pathogenic mutations

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670110

Characterizing antibody specificity to different protein morphologies by AFM

31 October 2018

1 reference

12 December 2020

Pathogenesis of Parkinson's disease

1 reference

12 December 2020

1 reference

12 December 2020

Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments

1 reference

12 December 2020

Secondary structure of alpha-synuclein oligomers: characterization by raman and atomic force microscopy

1 reference

12 December 2020

Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M806559200

1 reference

26 July 2017

1 reference

26 July 2017

1 reference