(Q33401270)

26 July 2017

1 reference

title

Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis (English)

1 reference

26 July 2017

1

Manfred T Reetz

1 reference

26 July 2017

Joaquin Sanchis

3

1 reference

ORCID Public Data File 2021

author name string

Daniel Kahakeaw

series ordinal

2

1 reference

26 July 2017

9 December 2008

1 reference

26 July 2017

1 reference

26 July 2017

5

1 reference

26 July 2017

115-122

1 reference

26 July 2017

2

1 reference

Tailoring new enzyme functions by rational redesign

26 July 2017

1 reference

Directed evolution of biocatalytic processes

21 January 2018

1 reference

Recent advances in biocatalysis by directed enzyme evolution

21 January 2018

1 reference

Advances in laboratory evolution of enzymes

21 January 2018

1 reference

Controlling the enantioselectivity of enzymes by directed evolution: practical and theoretical ramifications

21 January 2018

1 reference

Novel methods for directed evolution of enzymes: quality, not quantity

21 January 2018

1 reference

Enzyme optimization: moving from blind evolution to statistical exploration of sequence-function space

21 January 2018

1 reference

A genetic selection system for evolving enantioselectivity of enzymes

21 January 2018

1 reference

A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.

21 January 2018

1 reference

Learning from directed evolution: theoretical investigations into cooperative mutations in lipase enantioselectivity

21 January 2018

1 reference

Learning from directed evolution: Further lessons from theoretical investigations into cooperative mutations in lipase enantioselectivity

21 January 2018

1 reference

Inverting enantioselectivity of Burkholderia cepacia KWI-56 lipase by combinatorial mutation and high-throughput screening using single-molecule PCR and in vitro expression

21 January 2018

1 reference

Combinatorial manipulation of three key active site residues in glycinamide ribonucleotide transformylase

21 January 2018

1 reference

Mutations in distant residues moderately increase the enantioselectivity of Pseudomonas fluorescens esterase towards methyl 3bromo-2-methylpropanoate and ethyl 3phenylbutyrate

21 January 2018

1 reference

Active site engineering of the epoxide hydrolase from Agrobacterium radiobacter AD1 to enhance aerobic mineralization of cis-1,2-dichloroethylene in cells expressing an evolved toluene ortho-monooxygenase

21 January 2018

1 reference

Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis

21 January 2018

1 reference

Expanding the substrate repertoire of a DNA polymerase by directed evolution

21 January 2018

1 reference

Directed evolution of O6-alkylguanine-DNA alkyltransferase for efficient labeling of fusion proteins with small molecules in vivo

21 January 2018

1 reference

Evolution in reverse: engineering a D-xylose-specific xylose reductase.

21 January 2018

1 reference

Iterative saturation mutagenesis (ISM) for rapid directed evolution of functional enzymes

21 January 2018

1 reference

Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases

21 January 2018

1 reference

Constructing and analyzing the fitness landscape of an experimental evolutionary process

21 January 2018

1 reference

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 January 2018

1 reference

Directed evolution of hybrid enzymes: Evolving enantioselectivity of an achiral Rh-complex anchored to a protein

21 January 2018

1 reference

Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing

21 January 2018

1 reference

Addressing the numbers problem in directed evolution

21 January 2018

1 reference

Cooperatively folded proteins in random sequence libraries

21 January 2018

1 reference

De novo proteins from designed combinatorial libraries

21 January 2018

1 reference

An active enzyme constructed from a 9-amino acid alphabet

21 January 2018

1 reference

Combinatorial mutagenesis to restrict amino acid usage in an enzyme to a reduced set

21 January 2018

1 reference

High solubility of random-sequence proteins consisting of five kinds of primitive amino acids

21 January 2018

1 reference

Modifying the chain-length selectivity of the lipase from Burkholderia cepacia KWI-56 through in vitro combinatorial mutagenesis in the substrate-binding site

21 January 2018

1 reference

Saturation mutagenesis of toluene ortho-monooxygenase of Burkholderia cepacia G4 for Enhanced 1-naphthol synthesis and chloroform degradation

21 January 2018

1 reference

Strategies and computational tools for improving randomized protein libraries

21 January 2018

1 reference

Mathematical expressions useful in the construction, description and evaluation of protein libraries.

21 January 2018

1 reference

Epoxide hydrolase-catalyzed enantioselective synthesis of chiral 1,2-diols via desymmetrization of meso-epoxides. lzhao@diversa.com

21 January 2018

1 reference

Evolving strategies for enzyme engineering

21 January 2018

1 reference

GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries

21 January 2018

1 reference

A biochemical genomics approach for identifying genes by the activity of their products.

21 January 2018

1 reference

Pooling for improved screening of combinatorial libraries for directed evolution

21 January 2018

1 reference

Miniaturising the laboratory in emulsion droplets

21 January 2018

1 reference

Enhancing the enantioselectivity of an epoxide hydrolase by directed evolution

21 January 2018

1 reference

Designing new Baeyer-Villiger monooxygenases using restricted CASTing

21 January 2018

1 reference

Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1039/B814862G

1 reference

26 July 2017

1 reference

PubMed ID

19156255