(Q33523814)

27 July 2017

title

The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA. (English)

1 reference

27 July 2017

6

Matthias Gaestel

0 references

Claus Johansen

Claus Johansen

5

0 references

Tue W Kragstrup

Tue Wenzel Kragstrup

3

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Lars F. Iversen

Lars Iversen

8

0 references

Søren Riis Paludan

4

Søren Riis Paludan

1 reference

27 July 2017

Kristian Otkjaer

1

1 reference

27 July 2017

Helmut Holtmann

2

1 reference

27 July 2017

Knud Kragballe

7

1 reference

27 July 2017

language of work or name

English

0 references

publication date

13 January 2010

1 reference

27 July 2017

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27 July 2017

volume

5

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27 July 2017

issue

1

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27 July 2017

page(s)

e8671

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

13 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis

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The p38 MAPK stress pathway as a tumor suppressor or more?

21 June 2018

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Control of mRNA decay by phosphorylation of tristetraprolin.

21 June 2018

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The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy

21 June 2018

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mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).

21 June 2018

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Functional analysis of KSRP interaction with the AU-rich element of interleukin-8 and identification of inflammatory mRNA targets

21 June 2018

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IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

21 June 2018

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BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis

21 June 2018

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Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines

21 June 2018

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Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

21 June 2018

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Cytokine induction of interleukin-24 in human peripheral blood mononuclear cells

21 June 2018

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Activation and signaling of the p38 MAP kinase pathway

21 June 2018

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The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.

21 June 2018

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Distinct domains of AU-rich elements exert different functions in mRNA destabilization and stabilization by p38 mitogen-activated protein kinase or HuR.

21 June 2018

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MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine

21 June 2018

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mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

21 June 2018

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The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

21 June 2018

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The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

21 June 2018

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Loss of MDA-7 expression with progression of melanoma

21 June 2018

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Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.

21 June 2018

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Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types

21 June 2018

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Interleukin 20: discovery, receptor identification, and role in epidermal function

21 June 2018

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AP-1 and C/EBP transcription factors contribute to mda-7 gene promoter activity during human melanoma differentiation

21 June 2018

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Identification of a novel ligand-receptor pair constitutively activated by ras oncogenes

21 June 2018

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Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression

21 June 2018

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

The dynamics of gene expression of interleukin-19 and interleukin-20 and their receptors in psoriasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Epidermal overexpression of interleukin-19 and -20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Differentiation of human melanoma cells through p38 MAP kinase is associated with decreased retinoblastoma protein phosphorylation and cell cycle arrest.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

Regulation of mda-7 gene expression during human melanoma differentiation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2801610

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

31 October 2018

1 reference

12 December 2020

IL-20 gene expression is induced by IL-1beta through mitogen-activated protein kinase and NF-kappaB-dependent mechanisms

1 reference

12 December 2020

The mitogen-activated protein kinases p38 and ERK1/2 are increased in lesional psoriatic skin

1 reference

12 December 2020

The involvement of p38 mitogen-activated protein kinase in the alpha-melanocyte stimulating hormone (alpha-MSH)-induced melanogenic and anti-proliferative effects in B16 murine melanoma cells

1 reference

12 December 2020

Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas

1 reference

12 December 2020

Increased DNA synthesis of uninvolved psoriatic epidermis is maintained in vitro

1 reference

12 December 2020

Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs

1 reference

12 December 2020

Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0008671

Identifiers

DOI

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27 July 2017

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27 July 2017

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