(Q44274480)

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Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients

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1 December 2017

Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients (English)

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1 December 2017

John Nemunaitis

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John Nemunaitis

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1 December 2017

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Alex W Tong

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Dan Su

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1 December 2017

Yuan Zhang

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Casey Cunningham

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Neil Senzer

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George Netto

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Dawn Rich

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Abner Mhashilkar

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Karen Parker

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Keith Coffee

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Rajagopal Ramesh

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1 December 2017

Suhendan Ekmekcioglu

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1 December 2017

Elizabeth A Grimm

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Jill van Wart Hood

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James Merritt

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Sunil Chada

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publication date

1 January 2005

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1 December 2017

Molecular Therapy

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1 December 2017

11

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1

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160-172

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1 December 2017

The melanoma differentiation associated gene mda-7 suppresses cancer cell growth

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro

1 reference

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7 January 2021

Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Mda-7/IL-24 induces apoptosis of diverse cancer cell lines through JAK/STAT-independent pathways

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Adenoviral transfer of mda-7 leads to BAX up-regulation and apoptosis in mesothelioma cells, and is abrogated by over-expression of BCL-XL

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The MUC gene family: their role in diagnosis and early detection of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

mda-7(IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer

1 reference

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7 January 2021

Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The family of IL-10-related cytokines and their receptors: related, but to what extent?

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Pilot trial of intravenous infusion of a replication-selective adenovirus (ONYX-015) in combination with chemotherapy or IL-2 treatment in refractory cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Gene therapy progress and prospects: adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Prognostic value of K-ras mutations, ras oncoprotein, and c-erb B-2 oncoprotein expression in adenocarcinoma of the lung

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Anti-tumorigenic effect of a K-ras ribozyme against human lung cancer cell line heterotransplants in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Cellular immune profile of patients with advanced cancer before and after taxane treatment

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Combination therapy of Ad-mda7 and trastuzumab increases cell death in Her-2/neu-overexpressing breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Adenoviral-mediated mda-7 expression suppresses DNA repair capacity and radiosensitizes non-small-cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.09.021

7 January 2021

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10.1016/J.YMTHE.2004.09.021

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 December 2017

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