(Q40667902)

English

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

scientific article published on February 2003

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 September 2017

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

9

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Paul Dent

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Europe PubMed Central

PubMed publication ID

22 September 2017

author name string

Zao-Zhong Su

1

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Europe PubMed Central

PubMed publication ID

22 September 2017

Irina V Lebedeva

2

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Europe PubMed Central

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22 September 2017

Devanand Sarkar

3

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Europe PubMed Central

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22 September 2017

Rahul V Gopalkrishnan

4

1 reference

Europe PubMed Central

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22 September 2017

Moira Sauane

5

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Europe PubMed Central

PubMed publication ID

22 September 2017

Carter Sigmon

6

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Europe PubMed Central

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22 September 2017

Adly Yacoub

7

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Kristoffer Valerie

8

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Europe PubMed Central

PubMed publication ID

22 September 2017

Paul B Fisher

10

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Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

1 February 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

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Europe PubMed Central

PubMed publication ID

22 September 2017

22

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Europe PubMed Central

PubMed publication ID

22 September 2017

8

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Europe PubMed Central

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22 September 2017

1164-1180

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Europe PubMed Central

PubMed publication ID

22 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206062

0 references

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Enhanced radiosensitivity of malignant glioma cells after adenoviral p53 transduction

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The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24.

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Adenovirus-mediated wild-type p53 expression induces apoptosis and suppresses tumorigenesis of experimental intracranial human malignant glioma

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Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes

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Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy

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Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2.

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Gene therapy for malignant gliomas

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Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents

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Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153

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Evidence for Distinct Kinase-Mediated Pathways in gadd Gene Responses

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Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells

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Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas

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Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells

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Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

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Gene therapy for cancer

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Mitochondria and apoptosis

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Creation of human tumour cells with defined genetic elements

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Regulated translation initiation controls stress-induced gene expression in mammalian cells

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Mammalian GADD34, an apoptosis- and DNA damage-inducible gene

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Potentials and limitations of adenovirus-p53 gene therapy for brain tumors

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Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties

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Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase 2.

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Adenovirus-mediated p53 gene therapy for human gliomas

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The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells

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1 reference

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10.1038/SJ.ONC.1206062

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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