(Q33539722)

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Molecular structures of quiescently grown and brain-derived polymorphic fibrils of the Alzheimer amyloid abeta9-40 peptide: a comparison to agitated fibrils

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scholarly article

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Europe PubMed Central

27 July 2017

Molecular structures of quiescently grown and brain-derived polymorphic fibrils of the Alzheimer amyloid abeta9-40 peptide: a comparison to agitated fibrils (English)

1 reference

Europe PubMed Central

27 July 2017

Alzheimer's disease

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Joan-Emma Shea

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Europe PubMed Central

27 July 2017

author name string

Michael T Bowers

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Europe PubMed Central

27 July 2017

publication date

5 March 2010

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Europe PubMed Central

27 July 2017

PLOS Computational Biology

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Europe PubMed Central

27 July 2017

6

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Europe PubMed Central

27 July 2017

3

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Europe PubMed Central

27 July 2017

e1000693

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Europe PubMed Central

27 July 2017

copyright license

Creative Commons Attribution 4.0 International

5 March 2010

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April 2022 Public Data File from Crossref

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Comparison of Alzheimer Abeta(1-40) and Abeta(1-42) amyloid fibrils reveals similar protofilament structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Measurement of amyloid fibril mass-per-length by tilted-beam transmission electron microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Two-dimensional IR spectroscopy and isotope labeling defines the pathway of amyloid formation with residue-specific resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Replica exchange simulations of the thermodynamics of Abeta fibril growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Modeling the Alzheimer Abeta17-42 fibril architecture: tight intermolecular sheet-sheet association and intramolecular hydrated cavities

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21 June 2018

New insights into the mechanism of Alzheimer amyloid-beta fibrillogenesis inhibition by N-methylated peptides

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21 June 2018

Protein folding by zipping and assembly

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21 June 2018

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

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21 June 2018

Structure and dynamics of parallel beta-sheets, hydrophobic core, and loops in Alzheimer's A beta fibrils

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21 June 2018

Calculation of protein-ligand binding affinities.

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21 June 2018

Molecular structure of amyloid fibrils: insights from solid-state NMR.

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21 June 2018

Protein misfolding, functional amyloid, and human disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Molecular dynamics simulations of Alzheimer's beta-amyloid protofilaments

1 reference

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21 June 2018

The Amber biomolecular simulation programs

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21 June 2018

Filaments of the Ure2p prion protein have a cross-beta core structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Stabilities and conformations of Alzheimer's beta -amyloid peptide oligomers (Abeta 16-22, Abeta 16-35, and Abeta 10-35): Sequence effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

The protofilament structure of insulin amyloid fibrils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Alzheimer's disease: genes, proteins, and therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models

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21 June 2018

Alzheimer's amyloid fibrils: structure and assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

Rank-order of potencies for inhibition of the secretion of abeta40 and abeta42 suggests that both are generated by a single gamma-secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

21 June 2018

The role of A beta 42 in Alzheimer's disease

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21 June 2018

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

1 reference

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21 June 2018

The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology.

1 reference

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21 June 2018

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

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21 June 2018

Amyloid beta-protein: monomer structure and early aggregation states of Abeta42 and its Pro19 alloform.

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21 January 2018

Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-beta protein.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000693

21 January 2018

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

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21 January 2018

Supramolecular structural constraints on Alzheimer's beta-amyloid fibrils from electron microscopy and solid-state nuclear magnetic resonance.

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21 January 2018

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

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21 January 2018

Comparison of simple potential functions for simulating liquid water

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https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000693

21 January 2018

Collective motion artifacts arising in long-duration molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000693

21 January 2018

Molecular dynamics simulations of Alzheimer Abeta40 elongation and lateral association.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2832665

31 October 2018

Molecular dynamics with coupling to an external bath

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https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000693

21 January 2018

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221247

12 December 2020

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10.1371/JOURNAL.PCBI.1000693

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Europe PubMed Central

27 July 2017

DBLP publication ID

journals/ploscb/WuBS10

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DBLP Dataset 2021-01-02

28 January 2021

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Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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