(Q33553383)

28 July 2017

title

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis (English)

1 reference

28 July 2017

0 references

1 reference

Vassiliki Kostourou

3

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Stephen Douglas Robinson

object named as

Stephen D Robinson

1

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John F Marshall

object named as

John F Marshall

8

0 references

Kairbaan Hodivala-Dilke

object named as

Kairbaan M Hodivala-Dilke

9

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author name string

Louise E Reynolds

2

1 reference

28 July 2017

Andrew R Reynolds

4

1 reference

28 July 2017

Rita Graça da Silva

5

1 reference

28 July 2017

Bernardo Tavora

6

1 reference

28 July 2017

Marianne Baker

7

1 reference

28 July 2017

language of work or name

English

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publication date

16 October 2009

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

284

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28 July 2017

issue

49

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28 July 2017

page(s)

33966-33981

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Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Structure-function analysis of the antiangiogenic ATWLPPR peptide inhibiting VEGF(165) binding to neuropilin-1 and molecular dynamics simulations of the ATWLPPR/neuropilin-1 complex

21 June 2018

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Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion

21 June 2018

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Molecular mapping and functional characterization of the VEGF164 heparin-binding domain

21 June 2018

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21 June 2018

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Integrin signaling is critical for pathological angiogenesis

21 June 2018

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21 June 2018

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21 June 2018

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Lessons from phase III clinical trials on anti-VEGF therapy for cancer

21 June 2018

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The neuropilins and their role in tumorigenesis and tumor progression

21 June 2018

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Vascular endothelial growth factor receptors: expression and function in solid tumors

21 June 2018

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21 June 2018

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Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: a computational model

21 June 2018

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Antiangiogenic activity of semisynthetic biotechnological heparins: low-molecular-weight-sulfated Escherichia coli K5 polysaccharide derivatives as fibroblast growth factor antagonists

21 June 2018

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Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system

21 June 2018

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Cre-lox-regulated conditional RNA interference from transgenes

21 June 2018

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Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

21 June 2018

1 reference

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VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

21 June 2018

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Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

21 June 2018

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Integrin and growth factor receptor crosstalk.

21 June 2018

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Differential expression of neuropilin-1 and neuropilin-2 in arteries and veins

21 June 2018

1 reference

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Vascular endothelial growth factor receptor-2 and neuropilin-1 form a receptor complex that is responsible for the differential signaling potency of VEGF(165) and VEGF(121)

21 June 2018

1 reference

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Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice

21 June 2018

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VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

21 June 2018

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Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

21 June 2018

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Angiogenesis in mice with chronic airway inflammation: strain-dependent differences

21 June 2018

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

21 June 2018

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21 June 2018

HGF/SF in angiogenesis

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Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis

21 June 2018

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p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

21 June 2018

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21 June 2018

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Tumor angiogenesis and the role of vascular cell integrin alphavbeta3.

21 June 2018

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Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

21 June 2018

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

21 June 2018

1 reference

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Quantitative in-vivo studies on angiogenesis in a rat sponge model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797167

Antiangiogenic combination tumor therapy blocking alpha(v)-integrins and VEGF-receptor-2 increases therapeutic effects in vivo

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.

21 January 2018

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Substituted benzocyloheptenes as potent and selective alpha(v) integrin antagonists

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Stabilization of the retinal vascular network by reciprocal feedback between blood vessels and astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Abnormal lymphatic vessel development in neuropilin 2 mutant mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797167

Evidence from site-directed mutagenesis that the cytoplasmic domain of the beta3 subunit influences the conformational state of the alphaVbeta3 integrin ectodomain.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797167

A requirement for neuropilin-1 in embryonic vessel formation.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797167

Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

31 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.030700

Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling

21 January 2018

1 reference

12 December 2020

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

12 December 2020

In situ expression of beta 1, beta 3 and beta 4 integrin subunits in non-neoplastic endothelium and vascular tumours

1 reference

12 December 2020

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

1 reference

12 December 2020

Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells

1 reference

12 December 2020

Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor

1 reference

12 December 2020

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling

1 reference

12 December 2020

Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in beta3-integrin-deficient mice

1 reference

12 December 2020

Primary mouse endothelial cell culture for assays of angiogenesis

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12 December 2020

Identifiers

DOI

10.1074/JBC.M109.030700

1 reference

28 July 2017

1 reference

28 July 2017

1 reference