(Q33567691)

28 July 2017

Acetylation of WRN protein regulates its stability by inhibiting ubiquitination (English)

1 reference

28 July 2017

protein ubiquitination

1 reference

Kai Li

1

1 reference

28 July 2017

Rui Wang

2

1 reference

28 July 2017

Enerlyn Lozada

3

1 reference

28 July 2017

Wei Fan

4

1 reference

28 July 2017

David K Orren

5

1 reference

28 July 2017

Jianyuan Luo

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

23 April 2010

1 reference

28 July 2017

1 reference

28 July 2017

5

1 reference

28 July 2017

4

1 reference

28 July 2017

e10341

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

start time

23 April 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

PCAF acetylates {beta}-catenin and improves its stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Acetylation regulates WRN catalytic activities and affects base excision DNA repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

The role of WRN in DNA repair is affected by post-translational modifications.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Cellular dynamics and modulation of WRN protein is DNA damage specific

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Pathways and functions of the Werner syndrome protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Control of Smad7 stability by competition between acetylation and ubiquitination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

DNA damage-induced translocation of the Werner helicase is regulated by acetylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Werner syndrome cells are sensitive to DNA cross-linking drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Positional cloning of the Werner's syndrome gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

The Bloom's syndrome gene product is homologous to RecQ helicases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Acetylation of p53 inhibits its ubiquitination by Mdm2.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859066

Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20428248

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20428248

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0010341

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference