(Q33570348)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

β-globin gene transfer to human bone marrow for sickle cell disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

0 references

4

1 reference

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5 March 2020

Donald B. Kohn

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Satiro N De Oliveira

15

1 reference

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5 March 2020

Thomas Coates

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Zulema Romero

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Fabrizia Urbinati

2

1 reference

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5 March 2020

Sabine Geiger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jennifer Wherley

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Michael L Kaufman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Roger P Hollis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Rafael Ruiz de Assin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Shantha Senadheera

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Arineh Sahagian

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Xiangyang Jin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Alyse Gellis

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Xiaoyan Wang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

David Gjertson

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Pamela Kempert

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Sally Shupien

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Hisham Abdel-Azim

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Mark C Walters

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Herbert J Meiselman

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Rosalinda B Wenby

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Theresa Gruber

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Victor Marder

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

1 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

5 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4011030/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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21 June 2018

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Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients

21 June 2018

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21 June 2018

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Hematopoietic stem cell transplantation for sickle cell disease: current practice and emerging trends

21 June 2018

1 reference

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Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration

21 June 2018

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21 June 2018

1 reference

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Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease

21 June 2018

1 reference

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Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing

21 June 2018

1 reference

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Insulators and promoters: closer than we think

21 June 2018

1 reference

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

21 June 2018

1 reference

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Blood and marrow transplantation for sickle cell disease: overcoming barriers to success

21 June 2018

1 reference

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Granulocyte colony-stimulating factor (G-CSF) administration in individuals with sickle cell disease: time for a moratorium?

21 June 2018

1 reference

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A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction

21 June 2018

1 reference

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Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary

21 June 2018

1 reference

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Combinatorial incorporation of enhancer-blocking components of the chicken beta-globin 5'HS4 and human T-cell receptor alpha/delta BEAD-1 insulators in self-inactivating retroviral vectors reduces their genotoxic potential

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of beta-thalassemia

21 June 2018

1 reference

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Current status of globin gene therapy for the treatment of beta-thalassaemia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Locus control region elements HS1 and HS4 enhance the therapeutic efficacy of globin gene transfer in beta-thalassemic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Mixed haematopoietic chimerism for sickle cell disease prevents intravascular haemolysis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

CancerGenes: a gene selection resource for cancer genome projects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

21 June 2018

1 reference

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Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia

21 June 2018

1 reference

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A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin

21 June 2018

1 reference

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Transcription start regions in the human genome are favored targets for MLV integration

21 June 2018

1 reference

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Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods

21 June 2018

1 reference

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Correction of sickle cell disease in transgenic mouse models by gene therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

A chromatin insulator protects retrovirus vectors from chromosomal position effects

21 June 2018

1 reference

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Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

21 June 2018

1 reference

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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

A third-generation lentivirus vector with a conditional packaging system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Recombinant human hemoglobins designed for gene therapy of sickle cell disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Hemoglobin S gelation and sickle cell disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Prediction of human mRNA donor and acceptor sites from the DNA sequence.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Characterization of murine hemopoietic-supportive (MS-1 and MS-5) and non-supportive (MS-K) cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Structural bases of the inhibitory effects of hemoglobin F and hemoglobin A2 on the polymerization of hemoglobin S

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Ex vivo generation of human red blood cells: a new advance in stem cell engineering

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Stable long-term donor engraftment following reduced-intensity hematopoietic cell transplantation for sickle cell disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

A post-transcriptional process contributes to efficient gamma-globin gene silencing in definitive erythroid cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

The Corfu deltabeta thalassemia deletion disrupts gamma-globin gene silencing and reveals post-transcriptional regulation of HbF expression

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Fatal sickle cell crisis after granulocyte colony-stimulating factor administration.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Regulated expression of the human beta-globin gene after retroviral transfer into murine and human hematopoietic cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011030

Circulating BFU-E in sickle cell anemia: relationship to percent fetal hemoglobin and BPA-like activity

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23863630

12 December 2020

inferred from PubMed ID database lookup

Long-term expression of the human beta-globin gene after retroviral transfer into pluripotent hematopoietic stem cells of the mouse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23863630

12 December 2020

inferred from PubMed ID database lookup

Granulocytosis causing sickle-cell crisis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23863630

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1172/JCI67930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23863630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23863630%20AND%20SRC:MED&resulttype=core&format=json