(Q33572732)

28 July 2017

title

Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression (English)

1 reference

28 July 2017

author

Charalambos Michaeloudes

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Ian M. Adcock

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Peter J. Barnes

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Kian Fan Chung

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

4

Pankaj K Bhavsar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Nicolas Mercado

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Colin Clarke

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

14 April 2014

1 reference

28 July 2017

published in

Journal of Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

4913-4920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

BET acetyl-lysine binding proteins control pathological cardiac hypertrophy

13 June 2020

cites work

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Neu-164 and Neu-107, two novel antioxidant and anti-myeloperoxidase compounds, inhibit acute cigarette smoke-induced lung inflammation

21 June 2018

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RXRα inhibits the NRF2-ARE signaling pathway through a direct interaction with the Neh7 domain of NRF2.

21 June 2018

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Oxidative stress and lipid peroxidation by-products at the crossroad between adipose organ dysregulation and obesity-linked insulin resistance

21 June 2018

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Disordered epigenetic regulation in MLL-related leukemia

21 June 2018

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Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation

21 June 2018

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21 June 2018

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Bromodomains as therapeutic targets

21 June 2018

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RelA Ser276 phosphorylation-coupled Lys310 acetylation controls transcriptional elongation of inflammatory cytokines in respiratory syncytial virus infection

21 June 2018

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

21 June 2018

1 reference

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The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

21 June 2018

1 reference

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Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Selective inhibition of BET bromodomains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Stress-activated cap'n'collar transcription factors in aging and human disease

21 June 2018

1 reference

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Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice

21 June 2018

1 reference

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Brd2 disruption in mice causes severe obesity without Type 2 diabetes

21 June 2018

1 reference

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A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1

21 June 2018

1 reference

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The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Immunology of asthma and chronic obstructive pulmonary disease

21 June 2018

1 reference

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Phosphorylation of Nrf2 in the transcription activation domain by casein kinase 2 (CK2) is critical for the nuclear translocation and transcription activation function of Nrf2 in IMR-32 neuroblastoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Oxidative stress and redox regulation of lung inflammation in COPD.

21 June 2018

1 reference

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Identification of transcription complexes that contain the double bromodomain protein Brd2 and chromatin remodeling machines

21 June 2018

1 reference

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The role of airway smooth muscle in the pathogenesis of airway wall remodeling in chronic obstructive pulmonary disease.

21 June 2018

1 reference

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Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011694

Activating transcription factor 3 is a novel repressor of the nuclear factor erythroid-derived 2-related factor 2 (Nrf2)-regulated stress pathway

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24733848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Corticosteroids affect nitric oxide generation, total free radicals production, and nitric oxide synthase activity in monocytes of asthmatic patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24733848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24733848

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1301984

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24733848%20AND%20SRC:MED&resulttype=core&format=json