(Q33577569)

28 July 2017

title

Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins (English)

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28 July 2017

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8

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28 July 2017

6

Daniel J Klionsky

0 references

Michaël Cerezo

3

object named as

Michaël Cerezo

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Patrick Brest

object named as

Patrick Brest

5

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Baharia Mograbi

object named as

Baharia Mograbi

9

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author name string

Amine Belaid

1

1 reference

28 July 2017

Papa Diogop Ndiaye

2

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28 July 2017

Laurence Cailleteau

4

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28 July 2017

Georges F Carle

7

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28 July 2017

publication date

26 November 2013

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28 July 2017

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28 July 2017

volume

10

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28 July 2017

issue

2

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28 July 2017

page(s)

201-208

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describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5396087/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Increased expression of ATG10 in colorectal cancer is associated with lymphovascular invasion and lymph node metastasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors.

28 July 2018

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TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Src-dependent autophagic degradation of Ret in FAK-signalling-defective cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Internalized gap junctions are degraded by autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

28 July 2018

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Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade

28 July 2018

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Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome

28 July 2018

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β-catenin is dynamically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Plasma membrane contributes to the formation of pre-autophagosomal structures

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Disruption of lysosome function promotes tumor growth and metastasis in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Lysosomal degradation of RhoH protein upon antigen receptor activation in T but not B cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy inhibition in combination cancer treatment.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Oncogenic ras-induced down-regulation of autophagy mediator Beclin-1 is required for malignant transformation of intestinal epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

The ubiquitin-like protein LC3 regulates the Rho-GEF activity of AKAP-Lbc

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Coordination of Rho GTPase activities during cell protrusion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy suppresses tumorigenesis through elimination of p62

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Inhibition of Rho kinases enhances the degradation of mutant huntingtin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

The underrecognized progressive nature of N370S Gaucher disease and assessment of cancer risk in 403 patients

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Regulation of cytokinesis by Rho GTPase flux

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Extracellular matrix regulation of autophagy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy in the Pathogenesis of Disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Induction of autophagy during extracellular matrix detachment promotes cell survival

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Role of autophagy in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Autophagy suppresses tumor progression by limiting chromosomal instability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5396087

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

28 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK).

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Downregulation of active IKK beta by Ro52-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

DEDD interacts with PI3KC3 to activate autophagy and attenuate epithelial-mesenchymal transition in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Blocking autophagy prevents bortezomib-induced NF-κB activation by reducing I-κBα degradation in lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

An ECT2-centralspindlin complex regulates the localization and function of RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27198

LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24300375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24300375

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/AUTO.27198

1 reference

28 July 2017

1 reference

28 July 2017

1 reference