(Q33602978)

28 July 2017

title

GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response (English)

1 reference

28 July 2017

0 references

5

John C Boothroyd

1 reference

28 July 2017

Anjali J Shastri

1

1 reference

28 July 2017

Nicole D Marino

series ordinal

2

1 reference

28 July 2017

Magdalena Franco

series ordinal

3

1 reference

28 July 2017

Melissa B Lodoen

series ordinal

4

1 reference

28 July 2017

language of work or name

English

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publication date

7 April 2014

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28 July 2017

published in

Infection and Immunity

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28 July 2017

volume

82

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28 July 2017

issue

6

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28 July 2017

page(s)

2595-2605

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4019154/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.

1 reference

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A nucleotide sugar transporter involved in glycosylation of the Toxoplasma tissue cyst wall is required for efficient persistence of bradyzoites

21 June 2018

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Host cell subversion by Toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression.

21 June 2018

1 reference

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Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

21 June 2018

1 reference

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Modulation of innate immunity by Toxoplasma gondii virulence effectors

21 June 2018

1 reference

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Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity

21 June 2018

1 reference

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A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins

21 June 2018

1 reference

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The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

21 June 2018

1 reference

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Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts

21 June 2018

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Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance

21 June 2018

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Differential gene expression in mice infected with distinct Toxoplasma strains

21 June 2018

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Strain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts

21 June 2018

1 reference

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Identification of tissue cyst wall components by transcriptome analysis of in vivo and in vitro Toxoplasma gondii bradyzoites

21 June 2018

1 reference

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The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries.

21 June 2018

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Monocyte recruitment during infection and inflammation

21 June 2018

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Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

21 June 2018

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Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

21 June 2018

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Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.

21 June 2018

1 reference

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Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

21 June 2018

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A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Gr1(+) inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Protein-protein interactions identified by pull-down experiments and mass spectrometry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Polymorphic secreted kinases are key virulence factors in toxoplasmosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Recruitment of Gr-1+ monocytes is essential for control of acute toxoplasmosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Infection of human astrocytes and glioblastoma cells with Toxoplasma gondii: monocyte chemotactic protein-1 secretion and chemokine expression in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma evacuoles: a two-step process of secretion and fusion forms the parasitophorous vacuole

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma gondii induces the secretion of monocyte chemotactic protein-1 in human fibroblasts, in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Development of gametes and oocysts in cats fed cysts derived from cloned trophozoites of Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Nuclear factor-kappa B plays a major role in the regulation of chemokine expression of HeLa cells in response to Toxoplasma gondii infection

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019154

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24711568

12 December 2020

inferred from PubMed ID database lookup

Toxoplasma gondii: genetic recombination between drug resistant mutants

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24711568

12 December 2020

inferred from PubMed ID database lookup

Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24711568

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/IAI.01339-13

1 reference

28 July 2017

1 reference

28 July 2017

1 reference