(Q33604502)

28 July 2017

Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes (English)

1 reference

28 July 2017

0 references

Michael B Wheeler

5

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author name string

Hongfang Lu

1

1 reference

28 July 2017

Vasilij Koshkin

2

1 reference

28 July 2017

Emma M Allister

3

1 reference

28 July 2017

Armen V Gyulkhandanyan

4

1 reference

28 July 2017

language of work or name

English

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publication date

10 November 2009

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28 July 2017

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28 July 2017

59

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28 July 2017

2

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28 July 2017

448-459

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

28 July 2017

start time

28 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function

21 June 2018

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TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells

21 June 2018

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21 June 2018

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21 June 2018

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Mitochondrial dysfunction in pancreatic beta-cells in Type 2 diabetes

21 June 2018

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The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach

21 June 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 June 2018

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Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell

21 June 2018

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Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

21 June 2018

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Reactive oxygen species in mitochondria-mediated cell death

21 June 2018

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21 June 2018

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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

21 June 2018

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The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy

21 June 2018

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Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes

21 June 2018

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Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells

21 June 2018

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The mitochondrial inner membrane protein mitofilin controls cristae morphology

21 June 2018

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

21 June 2018

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Mitochondrial diabetes: molecular mechanisms and clinical presentation

21 June 2018

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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 June 2018

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21 June 2018

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21 June 2018

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

21 June 2018

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Mitochondrial oxidative stress. Physiologic consequences and potential for a role in aging

21 June 2018

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Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats

21 June 2018

1 reference

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The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

21 June 2018

1 reference

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Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

21 June 2018

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Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

21 June 2018

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Maternally inherited diabetes and deafness: a new diabetes subtype

21 June 2018

1 reference

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Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic beta-cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

21 June 2018

1 reference

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The ADP/ATP ratio: A novel predictive assay for quality assessment of isolated pancreatic islets.

21 June 2018

1 reference

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Leptin improves insulin resistance and hyperglycemia in a mouse model of type 2 diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Functional and molecular defects of pancreatic islets in human type 2 diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Association of the SOD2 Ala(-9)Val and SOD3 Arg213Gly polymorphisms with diabetic polyneuropathy in patients with diabetes mellitus type 1

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2809957

Insulin release in pancreatic islets by a glycolytic and a Krebs cycle intermediate: contrasting patterns of glyceraldehyde phosphate and succinate

30 October 2018

1 reference

12 December 2020

Dependence on NADH produced during glycolysis for beta-cell glucose signaling

1 reference

12 December 2020

In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243

1 reference

12 December 2020

Extramitochondrial ATP/ADP-ratios regulate cytochrome c oxidase activity via binding to the cytosolic domain of subunit IV

1 reference

12 December 2020

Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus

1 reference

12 December 2020

The Oscillatory Behavior of Pancreatic Islets from Mice with Mitochondrial Glycerol-3-phosphate Dehydrogenase Knockout

1 reference

12 December 2020

Ceramide Interaction with the Respiratory Chain of Heart Mitochondria†

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB09-0129

1 reference

28 July 2017

1 reference

28 July 2017

1 reference