(Q33412998)

26 July 2017

title

Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function (English)

1 reference

26 July 2017

1 reference

Dianxin Liu

4

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Barbara E. Corkey

object named as

Barbara E Corkey

8

0 references

Jingbo Pi

object named as

Jingbo Pi

1

0 references

author name string

Yushi Bai

2

1 reference

26 July 2017

Kiefer W Daniel

3

1 reference

26 July 2017

Otis Lyght

5

1 reference

26 July 2017

Diane Edelstein

6

1 reference

26 July 2017

Michael Brownlee

7

1 reference

26 July 2017

Sheila Collins

9

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26 July 2017

language of work or name

English

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publication date

26 February 2009

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26 July 2017

number of pages

9

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inferred from page(s)

published in

Endocrinology

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26 July 2017

volume

150

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26 July 2017

issue

7

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26 July 2017

page(s)

3040-3048

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Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species

26 July 2017

cites work

1 reference

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Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice

21 June 2018

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UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals

21 June 2018

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21 June 2018

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Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production

21 June 2018

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21 June 2018

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Recruitment of mitochondrial uncoupling protein UCP2 after lipopolysaccharide induction

21 June 2018

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21 June 2018

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21 June 2018

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Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells?

21 June 2018

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21 June 2018

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Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

1 reference

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Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 June 2018

1 reference

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Peroxynitrite reactions and formation in mitochondria

21 June 2018

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Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid.

21 June 2018

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Mice with targeted gene disruptions or gene insertions for diabetes research: problems, pitfalls, and potential solutions

21 June 2018

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Free radicals in the physiological control of cell function

21 June 2018

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Mitochondrial function in normal and diabetic beta-cells

21 June 2018

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21 June 2018

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 June 2018

1 reference

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

21 June 2018

1 reference

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

21 June 2018

1 reference

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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

21 June 2018

1 reference

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Gene microarray identification of redox and mitochondrial elements that control resistance or sensitivity to apoptosis

21 June 2018

1 reference

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The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Redox signaling: hydrogen peroxide as intracellular messenger

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Ten years of gene targeting: targeted mouse mutants, from vector design to phenotype analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Diet-induced changes in uncoupling proteins in obesity-prone and obesity-resistant strains of mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

21 June 2018

1 reference

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Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal beta-cells (HIT).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Markers of mouse macrophage development detected by monoclonal antibodies

21 June 2018

1 reference

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Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-kappaB activation and oxidative stress.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

The mitochondrial uncoupling-protein homologues.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

31 October 2018

1 reference

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D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

31 October 2018

1 reference

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Uncoupling Protein-2 Participates in Cellular Defense against Oxidative Stress in Clonal β-Cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2703519

Measuring H2O2 produced in response to cell surface receptor activation

31 October 2018

1 reference

12 December 2020

Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells

1 reference

12 December 2020

Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

1 reference

12 December 2020

Tumor necrosis factor increases mitochondrial oxidant production and induces expression of uncoupling protein-2 in the regenerating mice [correction of rat] liver

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2008-1642

1 reference

26 July 2017

1 reference

26 July 2017

1 reference