(Q44948928)

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D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways

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Europe PubMed Central

PubMed publication ID

7 December 2017

D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

author name string

Hiroki Takahashi

1

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Phuong Oanh T Tran

2

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Europe PubMed Central

PubMed publication ID

7 December 2017

Eric LeRoy

3

1 reference

Europe PubMed Central

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7 December 2017

Jamie S Harmon

4

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7 December 2017

Yoshito Tanaka

5

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7 December 2017

R Paul Robertson

6

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7 December 2017

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publication date

22 June 2004

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7 December 2017

Journal of Biological Chemistry

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7 December 2017

279

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Europe PubMed Central

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7 December 2017

36

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Europe PubMed Central

PubMed publication ID

7 December 2017

37316-37323

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

1 reference

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21 January 2018

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene

1 reference

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21 January 2018

Chronic exposure of betaTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

The stimulation of insulin secretion by d-glyceraldehyde correlates with its rate of oxidation in islet cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403070200

21 January 2018

Identifiers

10.1074/JBC.M403070200

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 December 2017

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