(Q33613593)

28 July 2017

title

CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose (English)

1 reference

28 July 2017

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Claudia B Catarino

10

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Joyce H You

object named as

Joyce H You

8

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Stephen C Strom

object named as

Stephen Strom

7

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author name string

Amarjit S Chaudhry

1

1 reference

28 July 2017

Thomas J Urban

2

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28 July 2017

Jatinder K Lamba

3

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28 July 2017

Angela K Birnbaum

4

1 reference

28 July 2017

Rory P Remmel

5

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28 July 2017

Murali Subramanian

6

1 reference

28 July 2017

Dalia Kasperaviciute

9

1 reference

28 July 2017

Rodney A Radtke

11

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28 July 2017

Sanjay M Sisodiya

12

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28 July 2017

David B Goldstein

13

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28 July 2017

Erin G Schuetz

14

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28 July 2017

language of work or name

English

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publication date

23 October 2009

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Journal of Pharmacology and Experimental Therapeutics

28 July 2017

published in

1 reference

28 July 2017

volume

332

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28 July 2017

issue

2

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28 July 2017

page(s)

599-611

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Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin

21 June 2018

1 reference

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Novel CYP2C9 promoter variants and assessment of their impact on gene expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Epilepsy in the elderly: scope of the problem

21 June 2018

1 reference

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Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

High volume bioassays to assess CYP3A4-mediated drug interactions: induction and inhibition in a single cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

The impact of CYP2C9 genetics and oral contraceptives on cytochrome P450 2C9 phenotype

21 June 2018

1 reference

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Clinical significance of the cytochrome P450 2C19 genetic polymorphism

21 June 2018

1 reference

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Intergenic transcripts containing a novel human cytochrome P450 2C exon 1 spliced to sequences from the CYP2C9 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Phenytoin metabolism by human cytochrome P450: involvement of P450 3A and 2C forms in secondary metabolism and drug-protein adduct formation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

21 June 2018

1 reference

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Stereoselective 4'-hydroxylation of phenytoin: relationship to (S)-mephenytoin polymorphism in Japanese

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Allelic and functional variability of cytochrome P4502C9.

21 June 2018

1 reference

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Genetic analysis of the human cytochrome P450 CYP2C9 locus

21 June 2018

1 reference

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The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism

21 June 2018

1 reference

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The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Changes in gene expression induced by carbamazepine and phenytoin: testing the danger hypothesis

21 June 2018

1 reference

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Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver.

30 October 2018

1 reference

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CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose

30 October 2018

1 reference

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Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Induction of Human CYP2C9 by Rifampicin, Hyperforin, and Phenobarbital Is Mediated by the Pregnane X Receptor

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Relative contributions of CYP2C9 and 2C19 to phenytoin 4-hydroxylation in vitro: inhibition by sulfaphenazole, omeprazole, and ticlopidine

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

A common genetic basis for idiosyncratic toxicity of warfarin and phenytoin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

30 October 2018

Phenytoin auto-induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812115

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

30 October 2018

1 reference

12 December 2020

Extent of urinary excretion of p-hydroxyphenytoin in healthy subjects given phenytoin

1 reference

12 December 2020

Phenytoin auto-induction? Case reports

1 reference

12 December 2020

Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite

1 reference

12 December 2020

Use of Antiepileptic Medications In Nursing Homes

1 reference

12 December 2020

Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4

1 reference

12 December 2020

Phenytoin cumulation profiles

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.109.161026

1 reference

28 July 2017

1 reference

28 July 2017

1 reference