(Q33616867)

28 July 2017

title

Insights into the mode of action of the two-peptide lantibiotic haloduracin (English)

1 reference

28 July 2017

2

Wilfred A van der Donk

1 reference

28 July 2017

Trent J Oman

1

1 reference

28 July 2017

publication date

1 October 2009

1 reference

28 July 2017

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28 July 2017

volume

4

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28 July 2017

issue

10

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28 July 2017

page(s)

865-874

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Structure-activity relationship studies of the two-component lantibiotic haloduracin

28 July 2017

cites work

1 reference

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21 June 2018

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The importance of the leader sequence for directing lanthionine formation in lacticin 481.

21 June 2018

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Lantibiotics: peptides of diverse structure and function.

21 June 2018

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Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

21 June 2018

1 reference

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A lesson in efficient killing from two-component lantibiotics

21 June 2018

1 reference

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Lipid II as a target for antibiotics

21 June 2018

1 reference

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Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations

21 June 2018

1 reference

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Biosynthesis and mode of action of lantibiotics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Bacterial lantibiotics: strategies to improve therapeutic potential.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Effect of subtilin and nisin on the spores of Bacillus coagulans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Substrate analogues to study cell-wall biosynthesis and its inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Multiparameter flow cytometric analysis of antibiotic effects on membrane potential, membrane permeability, and bacterial counts of Staphylococcus aureus and Micrococcus luteus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Two-component anti-Staphylococcus aureus lantibiotic activity produced by Staphylococcus aureus C55

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Structure-activity study of the lantibiotic mutacin II from Streptococcus mutans T8 by a gene replacement strategy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Structure and biological activity of chemically modified nisin A species

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Protein engineering of lantibiotics.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Structure-activity relationships in the peptide antibiotic nisin: role of dehydroalanine 5.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Isolation and characterization of genetically engineered gallidermin and epidermin analogs.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Improvement of solubility and stability of the antimicrobial peptide nisin by protein engineering.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Construction of a Bacillus subtilis double mutant deficient in extracellular alkaline and neutral proteases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Conversion of Bacillus subtilis 168 to a subtilin producer by competence transformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Solution structures of nisin A and its two major degradation products determined by n.m.r

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Nisin Resistance in Clostridium botulinum Spores and Vegetative Cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Each peptide of the two-component lantibiotic lacticin 3147 requires a separate modification enzyme for activity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812937

Engineering a disulfide bond and free thiols in the lantibiotic nisin Z

30 October 2018

1 reference

12 December 2020

The tetracyclic lantibiotic actagardine. 1H-NMR and 13C-NMR assignments and revised primary structure

1 reference

12 December 2020

Extensive post-translational modification, including serine to D-alanine conversion, in the two-component lantibiotic, lacticin 3147

1 reference

12 December 2020

Promising antibiotic candidate identified

1 reference

12 December 2020

Activity of nisin against Streptococcus pneumoniae, in vitro, and in a mouse infection model

1 reference

12 December 2020

The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II

1 reference

12 December 2020

Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125

1 reference

12 December 2020

Identifiers

DOI

10.1021/CB900194X

1 reference

28 July 2017

1 reference

28 July 2017

1 reference