(Q33629153)

28 July 2017

title

Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events (English)

1 reference

28 July 2017

Amanda P Struckhoff

1

1 reference

28 July 2017

Jason R Vitko

2

1 reference

28 July 2017

Manish K Rana

3

1 reference

28 July 2017

Carter T Davis

4

1 reference

28 July 2017

Kamau E Foderingham

5

1 reference

28 July 2017

Chi-Hsin Liu

6

1 reference

28 July 2017

Lyndsay Vanhoy-Rhodes

7

1 reference

28 July 2017

Steven Elliot

8

1 reference

28 July 2017

Yun Zhu

9

1 reference

28 July 2017

Matt Burow

10

1 reference

28 July 2017

Rebecca A Worthylake

11

1 reference

28 July 2017

language of work or name

English

0 references

publication date

5 January 2010

1 reference

28 July 2017

published in

Journal of Cell Science

1 reference

28 July 2017

volume

123

1 reference

28 July 2017

issue

Pt 3

1 reference

28 July 2017

page(s)

401-412

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2816185/fullTextXML

inferred from PubMed Central ID database lookup

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21 June 2018

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21 June 2018

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21 June 2018

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Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells

21 June 2018

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SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia

21 June 2018

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21 June 2018

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The tumor cell-host organ interface in the early onset of metastatic organ colonisation

21 June 2018

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Stepping out of the flow: capillary extravasation in cancer metastasis

21 June 2018

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Rho/ROCK and myosin II control the polarized distribution of endocytic clathrin structures at the uropod of moving T lymphocytes.

21 June 2018

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Organ selectivity in metastasis: regulation by chemokines and their receptors

21 June 2018

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21 June 2018

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CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells

21 June 2018

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21 June 2018

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Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Rho activation regulates CXCL12 chemokine stimulated actin rearrangement and restitution in model intestinal epithelia.

21 June 2018

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Integrin regulation of lymphocyte trafficking: lessons from structural and signaling studies

21 June 2018

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Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

21 June 2018

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Endothelial cell adhesion molecules and cancer progression

21 June 2018

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IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway

21 June 2018

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Lamellipodial actin mechanically links myosin activity with adhesion-site formation

21 June 2018

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Heparan sulfate on activated glomerular endothelial cells and exogenous heparinoids influence the rolling and adhesion of leucocytes.

21 June 2018

1 reference

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Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Intravascular cell-to-cell adhesive interactions and bone metastasis

21 June 2018

1 reference

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The Galpha13-Rho signaling axis is required for SDF-1-induced migration through CXCR4.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Tumor metastasis: mechanistic insights and clinical challenges

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Involvement of Rho/ROCK signalling in small cell lung cancer migration through human brain microvascular endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Paradoxical roles of the immune system during cancer development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

E1AF/PEA3 activates the Rho/Rho-associated kinase pathway to increase the malignancy potential of non-small-cell lung cancer cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Rho proteins in cell migration and metastasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Mechanical entrapment is insufficient and intercellular adhesion is essential for metastatic cell arrest in distant organs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Cdc42-MRCK and Rho-ROCK signalling cooperate in myosin phosphorylation and cell invasion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

The significance of cancer cell expression of the chemokine receptor CXCR4.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Adhesion mechanisms regulating the migration of monocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Rho-family GTPases: it's not only Rac and Rho (and I like it).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Rocks: multifunctional kinases in cell behaviour

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Tumour-cell invasion and migration: diversity and escape mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Leukocyte transendothelial migration: orchestrating the underlying molecular machinery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

RhoA is required for monocyte tail retraction during transendothelial migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Involvement of chemokine receptors in breast cancer metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Interplay between Rac and Rho in the control of substrate contact dynamics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Adhesion molecules in tumor metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Tumor cells caught in the act of invading: their strategy for enhanced cell motility.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Up-Regulation of Rho/ROCK Signaling in Sarcoma Cells Drives Invasion and Increased Generation of Protrusive Forces

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Myosin IIA regulates cell motility and actomyosin–microtubule crosstalk

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816185

Right on the spot. Chemokine triggering of integrin-mediated arrest of rolling leukocytes

30 October 2018

1 reference

12 December 2020

Chemokines and cancer

1 reference

12 December 2020

Rho signaling inhibitor, Y-27632, inhibits invasiveness of metastastic hepatocellular carcinoma in a mouse model

1 reference

12 December 2020

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

1 reference

12 December 2020

Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.052167

1 reference

28 July 2017

1 reference

28 July 2017

1 reference