(Q33643375)

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Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer

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8 March 2020

Co-expression network analysis identifies Spleen Tyrosine Kinase (SYK) as a candidate oncogenic driver in a subset of small-cell lung cancer (English)

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8 March 2020

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Daniel C. Liebler

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Jonathan E Clark

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Yong Zou

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Zuojian Tang

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Zhiguo Li

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Alexander Statnikov

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21 June 2018

Alternative splicing of SYK regulates mitosis and cell survival

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21 June 2018

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21 June 2018

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

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Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients

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The lymphoma-associated fusion tyrosine kinase ITK-SYK requires pleckstrin homology domain-mediated membrane localization for activation and cellular transformation

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Small cell lung cancer

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Identifiers

10.1186/1752-0509-7-S5-S1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24564859%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

DBLP publication ID

journals/bmcsb/UdyavarHCZTLLCSSLFEEMQ13

1 reference

DBLP Dataset 2021-01-02

28 January 2021

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24564859%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24564859%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

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