(Q39546323)

12 September 2017

title

Alternative splicing of SYK regulates mitosis and cell survival (English)

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alternative mRNA splicing, via spliceosome

12 September 2017

main subject

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Panagiotis Prinos

1

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12 September 2017

Daniel Garneau

2

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12 September 2017

Jean-François Lucier

3

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12 September 2017

Daniel Gendron

4

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12 September 2017

Sonia Couture

5

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12 September 2017

Marianne Boivin

6

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12 September 2017

Jean-Philippe Brosseau

7

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12 September 2017

Elvy Lapointe

8

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12 September 2017

Philippe Thibault

9

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12 September 2017

Mathieu Durand

10

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12 September 2017

Karine Tremblay

11

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12 September 2017

Julien Gervais-Bird

12

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12 September 2017

Hanad Nwilati

13

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12 September 2017

Roscoe Klinck

14

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12 September 2017

Benoit Chabot

15

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12 September 2017

Jean-Pierre Perreault

16

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12 September 2017

Raymund J Wellinger

17

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12 September 2017

Sherif Abou Elela

18

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12 September 2017

publication date

8 May 2011

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Nature Structural & Molecular Biology

12 September 2017

published in

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12 September 2017

volume

18

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12 September 2017

issue

6

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12 September 2017

page(s)

673-679

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Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

12 September 2017

cites work

1 reference

Alternative isoform regulation in human tissue transcriptomes

31 March 2020

1 reference

Understanding alternative splicing: towards a cellular code

31 March 2020

1 reference

Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines

31 March 2020

1 reference

Cancer-associated regulation of alternative splicing

31 March 2020

1 reference

Aberrant and alternative splicing in cancer

31 March 2020

1 reference

To metastasize or not? Selection of CD44 splice sites

31 March 2020

1 reference

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

31 March 2020

1 reference

Utilizing RNA interference to enhance cancer drug discovery

31 March 2020

1 reference

Multiple alternative splicing markers for ovarian cancer

31 March 2020

1 reference

Identification of alternative splicing markers for breast cancer

31 March 2020

1 reference

Exon-specific RNAi: a tool for dissecting the functional relevance of alternative splicing

31 March 2020

1 reference

Reprogramming Alternative Pre-messenger RNA Splicing through the Use of Protein-binding Antisense Oligonucleotides

31 March 2020

1 reference

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

31 March 2020

1 reference

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

31 March 2020

1 reference

Rapid turnover of mcl-1 couples translation to cell survival and apoptosis

31 March 2020

1 reference

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

31 March 2020

1 reference

Nucleocytoplasmic trafficking of the Syk protein tyrosine kinase

31 March 2020

1 reference

AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?

31 March 2020

1 reference

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

31 March 2020

1 reference

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

31 March 2020

1 reference

Mcl-1 is a potential therapeutic target in multiple types of cancer

31 March 2020

1 reference

31 March 2020

1 reference

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

31 March 2020

1 reference

Modification of alternative splicing of Mcl-1 pre-mRNA using antisense morpholino oligonucleotides induces apoptosis in basal cell carcinoma cells

31 March 2020

1 reference

The SYK tyrosine kinase: a crucial player in diverse biological functions

31 March 2020

1 reference

The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells

31 March 2020

1 reference

Progressive loss of Syk and abnormal proliferation in breast cancer cells

31 March 2020

1 reference

The Syk tyrosine kinase localizes to the centrosomes and negatively affects mitotic progression.

31 March 2020

1 reference

Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates alpha-tubulin on tyrosine

31 March 2020

1 reference

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas.

31 March 2020

1 reference

Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia.

31 March 2020

1 reference

Clinical significance of nuclear expression of spleen tyrosine kinase (Syk) in gastric cancer

31 March 2020

1 reference

Syk tyrosine kinase is linked to cell motility and progression in squamous cell carcinomas of the head and neck

31 March 2020

1 reference

Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia

31 March 2020

1 reference

Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT

31 March 2020

1 reference

Cell signalling and the control of pre-mRNA splicing.

31 March 2020

1 reference

Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function

31 March 2020

1 reference

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila

31 March 2020

1 reference

Exon Junction Complex Subunits Are Required to Splice Drosophila MAP Kinase, a Large Heterochromatic Gene

31 March 2020

1 reference

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

31 March 2020

1 reference

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

31 March 2020

1 reference

High-throughput quantification of splicing isoforms

31 March 2020

1 reference

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

31 March 2020

1 reference

Multiple and specific mRNA processing targets for the major human hnRNP proteins

31 March 2020

1 reference

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

31 March 2020

1 reference

Statistical methods for analysis of high-throughput RNA interference screens

31 March 2020

1 reference

Median absolute deviation to improve hit selection for genome-scale RNAi screens

31 March 2020

1 reference

Syk-dependent phosphorylation of microtubules in activated B-lymphocytes

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21552259

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alternative splicing disrupts a nuclear localization signal in spleen tyrosine kinase that is required for invasion suppression in breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21552259

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2040

1 reference

Dimensions Publication ID

12 September 2017

1013924498

0 references

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