(Q33644666)

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Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28476142%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28476142%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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Hemanth Kumar Kandikattu

3

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19 March 2020

author name string

Annayya R Aroor

1

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19 March 2020

Javad Habibi

2

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19 March 2020

Mona Garro-Kacher

4

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19 March 2020

Brady Barron

5

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19 March 2020

Dongqing Chen

6

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19 March 2020

Melvin R Hayden

7

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19 March 2020

Adam Whaley-Connell

8

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19 March 2020

Shawn B Bender

9

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19 March 2020

Thomas Klein

10

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19 March 2020

Jaume Padilla

11

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19 March 2020

James R Sowers

12

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19 March 2020

Bysani Chandrasekar

13

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19 March 2020

Vincent G DeMarco

14

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19 March 2020

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5 May 2017

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19 March 2020

Cardiovascular Diabetology

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19 March 2020

16

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19 March 2020

1

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19 March 2020

61

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19 March 2020

https://scigraph.springernature.com/pub.10.1186/s12933-017-0544-4

0 references

Effects of linagliptin and liraglutide on glucose- and angiotensin II-induced collagen formation and cytoskeleton degradation in cardiac fibroblasts in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Metformin inhibits aldosterone-induced cardiac fibroblast activation, migration and proliferation in vitro, and reverses aldosterone+salt-induced cardiac fibrosis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

The Cardiovascular Biology of Glucagon-like Peptide-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Cardiovascular risk with DPP-4 inhibitors: latest evidence and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Endothelial Mineralocorticoid Receptor Deletion Prevents Diet-Induced Cardiac Diastolic Dysfunction in Females

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Cardiovascular safety of linagliptin in type 2 diabetes: a comprehensive patient-level pooled analysis of prospectively adjudicated cardiovascular events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

A DPP-4 inhibitor suppresses fibrosis and inflammation on experimental autoimmune myocarditis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a mouse model of Western diet induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Pleiotropic effects of the dipeptidylpeptidase-4 inhibitors on the cardiovascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Prevention of obesity-induced renal injury in male mice by DPP4 inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

DPP-4 Inhibitors as Therapeutic Modulators of Immune Cell Function and Associated Cardiovascular and Renal Insulin Resistance in Obesity and Diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Diabetic cardiomyopathy: bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Mitochondria and Oxidative Stress in the Cardiorenal Metabolic Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Immunity as a link between obesity and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Sex and type 2 diabetes: obesity-independent effects on left ventricular substrate metabolism and relaxation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Interleukin-10 released by CD4(+)CD25(+) natural regulatory T cells improves microvascular endothelial function through inhibition of NADPH oxidase activity in hypertensive mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Mineralocorticoid receptors in vascular function and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Sex differences in obesity-related changes in left ventricular morphology: the Strong Heart Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

T-lymphocytes mediate left ventricular fibrillar collagen cross-linking and diastolic dysfunction in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

The development of heart failure in patients with diabetes mellitus and pre-clinical diastolic dysfunction a population-based study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Obesity and the risk of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Act1, an NF-kappa B-activating protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

21 June 2018

Impact of glucose intolerance and insulin resistance on cardiac structure and function: sex-related differences in the Framingham Heart Study

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Trends in lifetime risk and years of life lost due to diabetes in the USA, 1985-2011: a modelling study

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Safety and Tolerability of Linagliptin in Patients With Type 2 Diabetes: A Comprehensive Pooled Analysis of 22 Placebo-controlled Studies

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

DPP-4 inhibitor linagliptin ameliorates cardiovascular injury in salt-sensitive hypertensive rats independently of blood glucose and blood pressure

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Modulation of myocardial injury and collagen deposition following ischaemia-reperfusion by linagliptin and liraglutide, and both together

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Increased connective tissue growth factor relative to brain natriuretic peptide as a determinant of myocardial fibrosis.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Collagen cross-linking but not collagen amount associates with elevated filling pressures in hypertensive patients with stage C heart failure: potential role of lysyl oxidase.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

DPP-4 Inhibition by Linagliptin Attenuates Obesity-Related Inflammation and Insulin Resistance by Regulating M1/M2 Macrophage Polarization.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

BAY 11-7082, a nuclear factor-κB inhibitor, reduces inflammation and apoptosis in a rat cardiac ischemia-reperfusion injury model

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

IL-17 induces myocardial fibrosis and enhances RANKL/OPG and MMP/TIMP signaling in isoproterenol-induced heart failure.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Lentivirus mediated IL-17R blockade improves diastolic cardiac function in spontaneously hypertensive rats.

1 reference

https://api.crossref.org/works/10.1186%2FS12933-017-0544-4

21 January 2018

Impaired cardiac functional reserve in type 2 diabetic db/db mice is associated with metabolic, but not structural, remodelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5420102

30 October 2018

Preservation of Glucagon-Like Peptide-1 Level Attenuates Angiotensin II-Induced Tissue Fibrosis by Altering AT1/AT 2 Receptor Expression and Angiotensin-Converting Enzyme 2 Activity in Rat Heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DPP-4 inhibition attenuates cardiac dysfunction and adverse remodeling following myocardial infarction in rats with experimental diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The new insights from DPP-4 inhibitors: their potential immune modulatory function in autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/28476142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12933-017-0544-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28476142%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/s12933-017-0544-4

9 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28476142%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28476142%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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